An improved process for the preparation of an antibiotic substance, more specifically 7-{[2-(2-aminothiazol-4-yl)-2-syn-methoxyimino]acetamido}-3-{[(2,5-dih ydro-6-hyd roxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)thio]methyl} -3-cephem-4-carbo... R Monguzzi,S Menapace,P Anzaghi...