This chapter focuses on 4-hydroxybenzoate polyprenyltransferase from rat liver. 4-Hydroxybenzoate polyprenyltransferase is a key enzyme in ubiquinone synthesis because it catalyzes the step that brings together the precursor of the benzoquinone ring and the polyisoprenoid side chain. The substrates are 4...
英文名字 COQ2 (4-hydroxybenzoate Polyprenyltransferase, Mitochondrial, COQ2 Homolog, hCOQ2, Para-hydroxybenzoate--polyprenyltransferase, PHB:polyprenyltransferase, CL640)供应商 MyBioSource产品货号 MBS646054产品报价 ￥询价/0.1mg ￥询价/5x0.1mg ￥询价/其它规格产品说明书 点击查看...
The enzymes are apparently quite specific for the chain length of the isoprenoid precursors, which is in contrast to the broad substrate specificity of the polyprenyldiphosphate: 4-HB polyprenyltransferase from Escherichia coli.doi:10.1016/S0031-9422(96)00458-XRobert Boehm...
4-Hydroxybenzoate-polyprenyltransferase, an enzyme in ubiquinone biosynthesis, from Pseudomonas putida was partially purified by ion-exchange and gel filtration column chromatography. The enzyme required phospholipid as an essential factor for activity. Hexaprenyl pyrophosphate(-PP) and pentaprenyl-PP as ...
PHB:polyprenyltransferasedoi:10.1016/S0021-9258(19)45124-7Kazutaka MomoseHarry RudneyJournal of Biological ChemistryK. Momose, H. Rudney, 3-Polyprenyl-4-hydroxybenzoate synthesis in the inner membrane of mitochondria from p-hydroxybenzoate and isopentenylpyrophosphate. A demonstration of isoprenoid synthesis...
Polyprenylpyrophosphate: 4-hydroxybenzoate-polyprenyltransferase activity is highest in aerobically grown yeast cells and lowest in anaerobically grown cells. Its production is subject to catabolite repression in aerobic cells and the increase in its activity in anaerobic cells undergoing respiratory adaptation...
The ubiA and CoQ2 genes, which are involved in the synthesis of 4-hydroxybenzoate polyprenyltransferase, were cloned and overexpressed in A. cinnamomea. The results showed that ubiA and CoQ2 overexpression significantly increased AQ production in submerged fermentation. The overexpressing strain produced...