VM-26 was given as a 1 hour intravenous infusion on a weekly schedule of 130 mg/m脳 3, 150 mg/m脳 3, then 180 mg/muntil progression of disease. Of 12 evaluable patients, one had a complete response of 211 days duration, four had partial responses of 21+, 21+, 58 and 78 days...
Use of model organisms and in vitro techniques relevant to developmental biology and medicine are acceptable, as are translational human studies.doi:10.1203/00006450-197704000-00587Bleyer, W ArchieKrivit, WilliamChard, Ronald LHammond, DenmanPediatric Research...
Twenty-three patients, 16 with Hodgkin's Disease, 6 with lymphosarcoma and one with reticulum cell sarcoma were treated with the podophyllotoxin derivative 4鈥 -demethylepipodophyllotoxin 9-(4,6-o-2-thenylidene-beta-d-glucopyranoside); (VM-26; NSC-122819). All patients had far advanced, ...
Use of model organisms and in vitro techniques relevant to developmental biology and medicine are acceptable, as are translational human studies.doi:10.1203/00006450-197704000-00587W Archie BleyerWilliam KrivitRonald L ChardDenman HammondPediatric Research...