The analogues 5-phospho-pyridoxal-aminooxyacetate and 4-vinyl-pyridoxal 5-phosphate inhibit reduced 4-aminobutyrate aminotransferase reconstituted with pyridoxal 5-phosphate, but they do not affect the catalytic activity of the holoenzyme. The binding of the 5-phosphopyridoxal adducts to the holoenzyme ...
4-Aminobutyrate aminotransferase (ABAT; GABA-AT)Rat studies identified a GABA-AT inactivator that could help treat cocaine addiction. Further details on the research, next steps and licensing status are discussed in the article.Science-Business eXchangedoi:10.1038/scibx.2011.1358...
4-aminobutyrate aminotransferase(ABAT)antibody Cat.#: S0216 Rabbit Polyclonal Antibody Clone ID: polyclonal Swiss Prot: P80404 Mol Weight: 56.45kDa Size: 100ug Description 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly ...
The analogues 5-phospho-pyridoxal-aminooxyacetate and 4-vinyl-pyridoxal 5-phosphate inhibit reduced 4-aminobutyrate aminotransferase reconstituted with pyridoxal 5-phosphate, but they do not affect the catalytic activity of the holoenzyme. The binding of the 5-phosphopyridoxal adducts to the holoenzyme ...
1 1GBN Gabaculine irreversible inhibitor, (2.3 Å) & Homotetramer Gabaculine irreversible inhibitor of several aminotransferase. 2 1OAT PLP cofactor,(2.5 Å)&Homotetramer R180, E235, R413 probable active site by structure comparison studies with related transaminases 3 2BYJ PLPcofactor...
4-Aminobutyrate aminotransferase, which catalyzes the conversion of 4-aminobutyrate to succinic semialdehyde, is a key enzyme of the 4-aminobutyrate shunt. The amino acid sequence predicted from the cDNA sequence shows that the precursor protein consists of the mature enzyme of 473 amino acid ...
udomonas aeruginosa Involvement of 4-aminobutyrate aminotransferase in arginine biosynthesis and putrescine catabolism ofPseudomonas aeruginosaInvolvement of 4-aminobutyrate aminotransferase in arginine biosynthesis and putrescine catabolism ofPseudomonas aeruginosaadjustment of factors...
2) asparate aminotransferase 天冬氨酸氨基酸转移酶3) GABA transaminase γ-氨基丁酸转氨酶 1. Objective To examine the effects of sodium valproate(VPA) treatment and withdrawal on the expression of GA-BA transporter-3 (GAT-3) and GABA transaminase (GABA-T) mRNA in C6 glioma cells, and to ...
The protein coding sequence of the 4-aminobutyrate aminotransferase was amplified by polymerase chain reaction (PCR) from a previously cloned cDNA of pig b... SG Lee,TJ Choi,YT Kim - 《Journal of Microbiology & Biotechnology》 被引量: 24发表: 1996年 ...
E. (1989), Sequence of the cysteinyl-containing peptides of 4-aminobutyrate aminotransferase. European Journal of Biochemistry, 181: 397–401. doi: 10.1111/j.1432-1033.1989.tb14738.x Author Information Department of Biochemistry, University of Tennessee, Knoxville *Correspondence to J. E. Church...