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Full size image Interneurons showed a greater variability in both morphological and electrophysiological features. To facilitate targeting of interneurons for whole-cell recordings, we used Viaat-Cre/Ai9 mice (n = 47)29,38. Almost all labeled L4 neurons recorded from these mice (95.5%, 234...
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Full size image Inhibit CXCR4 and reduce macrophage glycolytic metabolism During the polarization process of M1 macrophages, glycolysis metabolism plays a dominant role [47,48]. Decreasing CXCR4 can enhance the mitochondrial metabolism of macrophages. Based on this, we speculate that CXCR4 can alter...
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Download: Download full-size image Fig. 1. Human smooth muscle cells (SMCs) express ACSL4-v1 mRNA. ACSL1, ACSL4, and ACSL5 mRNA levels were analyzed by real-time quantitative PCR in human aortic SMCs (A). The results were normalized to total RNA levels, and are expressed as mean copy...
ImageJ2x software had been adopted for determining the significant difference in protein expression. 2.21. Enzyme-linked immunosorbent assay Mouse cytokines in serum, culture supernatants and the colon extracts were measured with ELISA kits (Tongwei, China) for IL-1β (TW15343), IL-6 (TW11676)...
Sensory hypersensitivity is a common and debilitating feature of neurodevelopmental disorders such as Fragile X Syndrome (FXS). How developmental changes in neuronal function culminate in network dysfunction that underlies sensory hypersensitivities is u
The residue was treated with 100 mL of aq HCl solution (5 vol %) and extracted using CHCl3. After vacuum evaporation of the solvent (CHCl3), recrystallization of the residue using CHCl3-n-butanol gave monomer 1 as a white solid (11.67 g, yield 80%). Chemical formula: C46H40O4 (MW ...
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