26-Hydroxy-cholesterol3β-Hydroxy-5-cholestenoic acid3β-Hydroxy-5-cholenoic acidPig liver microsomes were found to catalyze the 7 alpha-hydroxylation of several potential bile acid precursors besides cholesterol. 26-Hydroxycholesterol, 3 beta-hydroxy-5-cholestenoic acid and 3 beta-hydroxy-5-chol...
Cholest-5-en-3-β-yloctanoat 1182-42-9 C35H60O2 2,(5-ALPHA)-CHOLESTEN-3-OL ACETATE C29H48O2 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL-7-ONE-3-ACETATE-METHYL ESTER C27H42O6 1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 3-GLUCOSIDURONATE C24H32O8 3,5-PREGNADIEN-3,17-DIOL-20-ONE...
The purified enzyme catalyzed the conversion of 7alpha-hydroxycholesterol, 7alpha,25-dihydroxycholesterol, 7alpha, 27-dihydroxycholesterol, and 3beta,7alpha-dihydroxy-5-cholestenoic acid into the corresponding 3-oxo-Delta4 compounds. The enzyme was inactive with C19 and C21 steroids as substrates. ...
The pathway from 7-oxocholesterol to 3β,7β-dihydroxy-5-cholenoic acid proceeds via the 27-carbon bile acid 3β,7β-dihydroxy-5-cholestenoic acid [15]. This bile acid is an agonist at LXRα and LXRβ receptors on neuronal cells, which, when activated, can promote the development of ...