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siRNAs best inhibiting CDR formation (more than 60% reduction relative to scrambled siEGFP) are enclosed into the light grey box. The oligo s95003 targeting Rab35, indicated in blue, is reported as a representative example. Red arrows indicate CDRs. Scale bar, 50 μm. b The siRNAs that...
18. “You’re always asking yourself, are you doing the best for your child? And other parents let you know if you’re not, just not in a direct way. There’s a sense of competition, which is ridiculous because you know deep down you’re all suffering.”–Tom Ellis ...
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(Fig.5a–g; Supplementary Movies2,3). Knockdown of all DENNd1s produced the greatest effect on sprouting behaviors, presumably because the GEF activity provided by DENNd1a/b was also lost (Fig.5d–f). Knocking down any given DENNd1 did not result in a compensatory increase in expression ...
Sewell said that it was hard to see Bunevacz’ family “living their best lives” online while his money was still missing. “We’re watching them continue to be princesses in the social media realm and it’s…just unbelievably frustrating,” he told the judge. Bunevacz wrote a ...