We found three metabolites (kynurenine, 3-OH-kynurenine, and anthranilate) from tryptophan pathways that increased H3K4 trimethylation and H2AS40 O-GlcNAcylation, resulting in upregulated gene expression at most loci, except those encoding pan-neural markers. Dietary supplementation of these three ...
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Comparative studies on eye colour mutants indicate that a first step in ommochrome synthesis is the binding of the precursor 3-OH-kynurenine to developing pigment granules. Both xanthommatin and ommin are present from the early beginning of eye differentiation, and exhibit different developmental ...
During the pharate pupal stage a massive accumulation of kynurenine and 3-OH-kynurenine is observed in the fat body of Ephestia k眉hniella . By injection it can be demonstrated that this organ is capable of sequestering at least 3-OH-kynurenine, the dominating tryptophan metabolite in Ephestia...
The absorption spectrum of the yellow substance shifted to that of 3-OH L-kynurenine (absorption maxima; 228, 267, and 368 nm) after hydrolysis with 尾-glucosidase [EC 3.2.1.21]. Concomitantly, its absorbances at 228 and 365 nm decreased; the spectra of both compounds intersect at 235, ...
The present invention is directed to a transparent medium incorporating the oxidative polymerization product of 3 -hydroxykynurenine, a synthetic version of the yellow-to-brown pigment that occurs in the ocular crystalline lens with age. Because this coloration in the ocular lens is believed to ...
Light filters using the oxidative polymerization product of 3-hydroxykynurenine (3-ohkyn)The present invention is directed to a transparent medium incorporating the oxidative polymerization product of 3-hydroxykynurenine, a synthetic version of the yellow-to-brown pigment that occurs in the ocular ...
JAMES GALLASGallas J (2004) Light filters using the oxidative polymerization product of 3-hydroxykynurenine (3-OHKyn). EP, US 6825975:B2
Gallas J (2004) Light filters using the oxidative polymerization product of 3-hydroxykynurenine (3-OHKyn). EP, US 6825975:B2US6825975 * Aug 27, 2002 Nov 30, 2004 Photoprotective Technologies, Inc. Light filters using the oxidative polymerization product of 3-Hydroxykynurenine (3-OHKyn)...
Gallas, JamesGallas J (2004) Light filters using the oxidative polymerization product of 3-hydroxykynurenine (3-OHKyn). EP, US 6825975:B2