Measurement of both plasma and urinary 3-methylhistidine (3-MH) levels has gained popularity because of its simplicity and economy, despite wide disagreement as to the validity of this method.doi:10.1007/978-3-662-22346-8_6David B. Pearlstone...
Epidermal Growth Factor Enhances Cellular TATA Binding Protein Levels and Induces RNA Polymerase I- and III-Dependent Gene Activity TATA binding protein (TBP) is a central transcription factor used by all three cellular RNA polymerases. Changes in the levels of TBP have been shown to ha... S ...
Mean fetal plasma 3-MH concentrations were 16.4 +/- 6.71 micrometers/100 ml, while maternal levels were 9.45 +/- 3.69 micrometers/100 ml. The fetal to maternal gradient was maintained between 1.6 to 1.7 during the course of maternal infusions of various AA. Since placental AA systems are ...
During the treatment their muscle strength, serum creatine kinase (CK) activity, serum levels of myoglobin (Mb), and urinary excretion of 3-methyl-histidine (3-MeH) and glycine (Gly) were measured serially. In all the patients, the motor function or muscle strength improved, and the serum ...
Food restriction: in the C/4 group ψ and m7Gua increased within a day by 22-25%, then fell to normal (ψ) or subnoimal (m7Gua, -18%) levels until day 5. m3His was elevated by from day 2 onwards. We conclude that there was a rapid transient breakdown of ribosomes and mRNA ...
ThyrotoxicosisMuscle protein breakdownUrinary 3-methylhistidine (3MH) excretion has been studied in 20 thyrotoxic patients before, during and after treatment. 3MH excretion was high on diagnosis and fell significantly, when the patients had been rendered euthyroid, to levels measured in a control ...
Vegetarian, ovo-lacto-vegetarian, and typical American diets provided no, trace, and customary dietary levels of Crn (and its precursors) and 3-MH. Twenty-four hour urine samples collected during days 3 and 4 of each diet were analyzed for Crn and 3-MH. In Experiment 2, ten women ate ...
These data suggest that either saturation or inhibition of acetylation pathways occurs with increasing levels of stress. Due to the disproportionate increases in NA-3-meH and percent NA-3-meH during endotoxemia, only total 3-meH should be used as an indicator of protein turnover in rats....
Other amino acids were not affected by the LF diet but they decreased significantly towards parturition and returned to precalving levels by 4weeks postcalving, except for leucine, glutamic acid, histidine and aspartic acid. Milk performance was not significantly different between the groups. The ...
After pre-column derivatization with OPA, analytical separation was achieved on a reversed-phase C18 column by a simple gradient between sodium propionate buffer and acetonitrile. the method is accurate, reproducible and sensitive, and allows the determination of urinary 3-MeHis levels in about 55 ...