Kynurenic acid(犬尿酸)是色氨酸的一种活性代谢物。 它是由色氨酸通过犬尿氨酸转氨酶 (KAT) 中间体通过犬尿氨酸形成。 犬尿酸是 NMDA 和 AMPA 受体以及 α7 烟碱型乙酰胆碱受体(nAChRs;EC50s = 235、101 和 7 µM)的拮抗剂。它也是芳烃受体 (AhR) 和 G 的激动剂 蛋白偶联受体 35(GPR35;EC50s = 1....
3-hydroxyquinaldic acidStreptomyces cyaneofuscatusdeep-sea actinobacteriaCantabrian SeaFractionation of the bioactive extract of a culture of the marine derived actinomycete Streptomyces cyaneofuscatus M-157 led to the isolation of the known 3-hydroxyquinaldic acid (4), its amide (5) and three new ...