Dialysate 3-OHBA and lactate levels in contracting and non-contracting muscles and in blood showed a significant increase after contraction (P<0.05) in diabetic rats. In control rats there was no significant change in dialysate 3-OHBA or the lactate concentration in contracting and non-contracting...
Background High levels of ketone bodies are associated with improved survival as observed with regular exercise, caloric restriction, and???most recently???treatment with sodium???glucose linked transporter 2 inhibitor antidiabetic drugs. In heart failure, indices of ketone body metabolism are upregul...
Genes and methods for optimizing levels of substrates employed in the biosynthesis of copolymers of 3-hydroxybutyrate (3HB) and 3-hydroxyvalerate (3HV) in plants and bacteria via manipulation of normal metabolic pathways using recombinan... KJ Gruys,TA Mitsky,GM Kishore,... - US 被引量: 14...
Oral beta-hydroxybutyrate supplementation in two patients with hyperinsulinemic hypoglycemia: monitoring of beta-hydroxybutyrate levels in blood and cerebrospinal fluid, and in the brain by in vivo magnetic resonance spectroscopy 1:CAS:528:DC%2BD38XmsFWms7Y%3D ...
The levels of 3-hydroxybutyrate were measured using an enzymati... E,M,Custer,... - 《American Journal of Clinical Pathology》 被引量: 45发表: 1983年 UNRECOGNIZED PERSISTENCE OF BETA-HYDROXYBUTYRATE IN DIABETIC KETOACIDOSIS We quantitated serial serum beta-hydroxybutyrate (β-OHB) levels using ...
Metabolomic profiling by nuclear magnetic resonance spectroscopy found that the serum levels of 2- hydroxybutyrate (2-HB), 3-hydoxybutyrate (3- HB), lactate, citrate, and tyrosine, were higher in patients who died within 3 months compared to those who were alive 3 months after onset of AHF...
(PHB synthesis and glycolysis), and the more distal carbon reserve metabolisms of lipid and glycogen synthesis. We found thatgdcinactivation reduced the metabolites levels in the TCA cycle, but increased the accumulation levels of PHB and pyruvate. Since,gdcinactivation has also been shown to ...
It was found that the expression of β-hydroxybutyrate dehydrogenase1 (BDH1) was significantly increased in the heart tissues of heart failure mouse models, however, the protein levels involved in fatty acid oxidation were down-regulated in the heart failure samples [4]. These result...
Following resolution, her insulin pump was replaced without further complications. Capillary blood levels of 3-hydroxybutyrate may be sensitive, early indicators of relapse of diabetic ketoacidosis, and are easily obtained.JohnDepartmentScottDepartmentBairdDepartmentSpringerCases Journal...
C. Analytical calculation of nuclear magnetic resonance indirect spin-spin coupling constants at the generalized gradient approx- imation and hybrid levels of density-functional theory. J. Chem. Phys 113, 9402–9409 (2000). 20 Anteunis, J. O., Tavernier, D. & Borremans, F. A review on ...