We found that 3-hydroxyanthranilic acid (3-HAA), the most potent metabolite, selectively eliminated activated T cells, which were stimulated with the bacterial superantigen staphylococcal enterotoxin A (SEA), but not resting T cells, by inducing apoptosis. We observed 3-HAA-induced depletion of ...
犬尿氨酸衍生物 3-HAA 是转录因子 YY1 的激动配体。| Shi, Z., et al. 2021. J Hematol Oncol. 14: 153. PMID: 34563230 产品名称产品编号规格价格数量收藏夹 3-Hydroxyanthranilic acid, 250 mg sc-216460 250 mg $66.00 3-Hydroxyanthranilic acid, 1 g ...
11, 12, 13, 14 Microglial kynurenines, such as 3-HK, 3-HAA, and quinolinic acid (Figure 1), have been implicated as neurotoxins in a number of neurologic diseases due to their free radical–generating and N-methyl-d-aspartic acid (NMDA) agonist activities.15, 16, 17, 18, 19 ...
The present invention relates to the use of a tryptophan metabolite, 3-hydroxyanthranilic acid (3-HAA) or a functional analogue thereof, for prophylactic and/or therapeutic treatment of mammals, in special humans, against hyperlipidemia and its cardiovascular complications, i.e. atheroma formation, ...
3-Hydroxyanthranilic acid (3-HAA), a metabolite of L-tryptophan, accumulates in monocyte-derived cells (THP-1),but not in other celllines tested(MRC9, H4, U373MG, Wil-NS), following immune stimulation that induces indoleamine 2,3-dioxygenase (IDO), a rate-limiting enzyme in the L-...
3-hydroxyanthranilic acid3-Hydroxyanthranilic acid (3-HAA) was determined by an immunologic method in the blood serum of 115 patients with various bladder tumors, five patients with hemorrhagic cystitis, 47 clinically healthy donors, and 44 patients with acute cystitis. The 3-HAA hapten was found ...
The present invention relates to the use of a tryptophan metabolite, 3-hydroxyanthranilic acid (3-HAA) or a functional analogue thereof, for prophylactic and/or therapeutic treatment of mammals, in special humans, against hyperlipidemia and its cardiovascular complications, i.e. atheroma formation, ...
3-Hydroxyanthranillic acid (3HAA) is one of the key metabolites from the tryptophan (TRP) metabolism pathway and is associated with aging, age-associated diseases, and healthy lifespan extension. This study aims to detect 3HAA in the sweat of healthy older adults using simple, high-...
3-Hydroxyanthranilic acid (3HAA) is one of the tryptophan metabolites along the kynurenine pathway and induces apoptosis in T cells. We investigated the mechanism of 3HAA-induced apoptosis in mouse thymocytes. The optimal concentration of 3HAA for apoptosis induction was 300-500 microM. The ...
Design and methods We evaluate the plasma levels of anthranilic acid (AA), 3-hydroxyanthranilic acid (3-HAA) and their possible relationship with CC-chemokines, Cu/Zn superoxide dismutase (Cu/Zn SOD) as the marker of oxidative status and high sensitivity C-reactive protein (hsCRP) as an ...