A green, efficient, and rapid procedure for the synthesis of 2-amino-3-cyano-1,4,5,6-tetrahydropyrano[3,2- c ]quinolin-5-one derivatives has been developed... M Lei,L Ma,L Hu - 《Tetrahedron Letters》 被引量: 0发表: 2011年 Dihydro-3H-chromeno(3,4-b) (4,7)phenanthrolin-3-...
Synonyms: 3-acetyl-5-amino-1,2,4-oxadiazole;1-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-3-methyl-1H-1,2,4-triazol-5(4H)-one;2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one;1-(5-amino-2,4-dichlorophenyl)-4-difluorometh...
repeated this type of reaction,and their X-ray structure analysis has shown thatinstead of the dihydropyrazoleIthe oxadiazole3awas formed (Scheme 1), obviously by an unusualmigration of hydrogen sulfide to the cyano group [2].It is noteworthy that during the reaction no smell ofhydrogen...
The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of disorders related to or affected by the 5-HT6 receptor.
Crystal structure of 4-(((2-(3-(1-(3-(3-cyanophenyl)-6-oxopyridazin-1(6H)-yl)ethyl)phenyl) pyrimidin-5-yl)oxy)methyl)-1-methylpiperidin-1-ium chloride monohydrate, C30H33N6O2Cl The crystal structure of 2-chloro-N-((2-chlorophenyl)carbamoyl)nicotinamide, C13H9Cl2N3O2 Crystal struc...
In the centrosymmetric title compound, C18H16N6O2S2, the 1,3,4-oxadiazole and the attached pyridinyl ring are twisted by 5.3(3)°. Q Liu,W Wei,Y Gao,... - 《Acta Crystallogr Sect E Struct Rep Online》 被引量: 9发表: 2011年 Separation of Molybdenite from Chalcopyrite in the Presence...
Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions th
The invention relates to 2-substituted 7-amino-azolopyrimidine of formula (I), wherein substituents have the following meanings: R1 is hydrogen, halogen, cyano, alkyl, halogenalkyl, alkenyl, alkynyl, Cycloalkyl, alkoxy, alkoxyalkyl, benz... Schwogler,Anja,Strathmann,... - EP 被引量: 72发...
Crystal structures of two 4H-chromene derivatives: 2-amino-3-cyano-4-(3,4-dichlorophenyl)-7-hydroxy-4H-benzo[1,2-b]pyran 1,4-dioxane monosolvate and 2-amin... In the title compounds, C16H9Cl2N2O2·C4H8O2 and C16H9Cl2N2O2, the bicyclic 4H-chromene cores are nearly planar with maximu...
Thus a series of novel 4-substituted N-(5-amino-1H-1,2,4-triazol-3-yl)pyridine-3-sulfonamides have been synthesized by multistep reactions starting from 4-chloropyridine-3-sulfonamide via N -cyano-N-[(4- substitutedpyridin-3-yl)sulfonyl]carbamimidothioates which were further converted with...