研究显示3-羟基丁酸(3HB)及其衍生物3-羟基丁酸甲酯(3HBME)可以有效抑制由模拟微重力环境导致的小鼠骨质疏松,促进骨的微观结构的恢复,使骨体积百分数提高3倍,骨小梁厚度及数目分别提高1.3倍和2.2倍.口服3HB或3HBME 4周后,股骨的强度提高了20%.微重力环境下,破骨细胞的活性异常增强,导致骨吸收增加而产生骨质疏松...
3、TY物活性 (R)-3-Hydroxybutanoic acid种代谢物,由 3-羟 丁酸脱氢酶催化酸酯获得。IC & Target Human Endogenous Metabolite体外研究 (R)-3-Hydroxybutanoic acid (D-3-Hydroxybutyric acid) is a metabolite, and converted from acetoacetic acid. Enhancedhepatic fatty acid oxidation results in the increased...