A sensitive and selective ultra-high performance liquid chromatography–tandem mass spectrometry assay was successfully developed for the determination of cotinine, trans-3′-hydroxycotinine, and their glucuronides in urine. The rapid and simple sample preparation makes this assay suitable for high ...
SPE-LC-MS/MS Method for the Determination of Nicotine, Cotinine, and Trans-3-hydroxycotinine in Urine A liquid chromatography tandem mass spectrometry method for nicotine,cotinine, and trans-3-hydroxycotinine in urine has been developed. UsingThermo ScientificTM SOLATM CX cartridges or plates, samp...
The intake of nicotine can be determined by the content of its metabolites in the urine, in particular by the content of trans-3'-hydroxycotinine (tH-Cot). A joint assessment of the concentrations of trans-3'-hydroxycotinine and MAs in urine allows obtaining selective information about effects...
Speaker 3:But if they did not quit smoking in six months, any money they put into that account would disappear. So if they fail urine test in six months for nicotine or cotinine, so it was like a real test. You can't just lie and say, I quit smoking. And...
The intake of nicotine can be determined by the content of its metabolites in the urine, in particular by the content of trans-3'-hydroxycotinine (tH-Cot). A joint assessment of the concentrations of trans-3'-hydroxycotinine and MAs in urine allows obtaining selective information about effects...
cotinine, trans-3-hydroxycotinine, urine, GCMS, SPEA gas chromatography–mass spectrometry method was developed and validated for the simultaneous automated solid-phase extraction and quantification of cotinine and trans-3-hydroxycotinine in human urine. Good linearity was observed over the concentration...
We measured blood vitamin A, C, E (alpha-, beta- and gamma-tocopherol), coenzyme Q10 and urine cotinine concentrations in nonsmokers and smokers. Twenty-one healthy nonsmokers and 24 healthy smokers were included in this study. Smoking status was assessed with a self-reported questionnaire. ...
A liquid chromatography tandem mass spectrometry method for nicotine,cotinine, and trans-3-hydroxycotinine in urine has been developed. UsingThermo ScientificTM SOLATM CX cartridges or plates...
Neurath GB, Dunger M, Orth D, Pein FG (1987) Trans-3 -hydroxycotinine as a main metabolite in urine of smokers. Int Arch Occup Environ Health 59(2):199-201Neurath, G.B., Dunger, M., Orth, D. et al (1987) Trans-3’-hydroxycotinine as a main metabolite in urine of smokers. ...
In this work, we have developed an effective system of two‐dimensional liquid chromatography coupled with tandem mass spectrometry for high‐throughput simultaneous determination of 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol and cotinine in smoker's urine. The strong cation‐exchange and ...