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Although defects in intracellular calcium homeostasis are known to play a role in the pathogenesis of Parkinson’s disease (PD), the underlying molecular mechanisms remain unclear. Here, we show that loss of PTEN-induced kinase 1 (PINK1) and Parkin leads
The mineral dust-induced gene (MDIG) comprises a conserved JmjC domain and has the ability to demethylate histone H3 lysine 9 trimethylation (H3K9me3). Previous studies have indicated the significance of MDIG in promoting cell proliferation by modulating
[6]O'Keefe JH Jr, Abuissa H, Sastre A, et al. Effects of omega-3 fatty acids on resting heart rate, heart rate recovery after exercise, and heart rate variability in men with healed myocardial infarctions and depressed ejection fractions. Am J Cardiol. 2006;97(8):1127-30. doi: 10.10...
JÖAI__Jahreshefte des Österreichischen Archäologischen Instituts in Wien__《维也纳奥地利考古学研究所年刊》 Joannes Damascenus__大马士革的若望/约翰[Ἰωάννης ὁ Δαμασκηνός]* ___Vita Barlaam et Ioasaph__《贝尔拉姆与约瑟法特》[Βαρλαὰμ καὶ...
For a long time, PLS3 (plastin 3, also known as T-plastin or fimbrin) has been considered a rather inconspicuous protein, involved in F-actin-binding and -
The WT/heterozygous and Top3β-KO mice underwent MRI scanning using a 7 T/30 cm preclinical Bruker Biospec scanner (Bruker Biospin, Ettlingen, Germany); n = 8 per group. Data were acquired when the mice were 2–3 months of age. A 72 mm diameter birdcage-design resonator was ...
Poulose BK, Holzman MD, Zhu Y, et al National variations in morbid obesity and bariatric surgery use. J Am Coll Surg. 2005;201(1):77–84. ArticlePubMed Angrisani L, Di Lorenzo N, Favretti F, et al The Italian Group for LAP-BAND: predictive value of initial body mass index for weig...
In IDEFICS, 16 228 children aged 2–9 years were examined in a population-based baseline survey in eight European countries ranging from North to South and from East to West (Belgium, Cyprus, Estonia, Germany, Hungary, Italy, Spain and Sweden) from autumn 2007 to spring 2008. This baseline...
Liverpool team news, focus Kelleher, Quansah and Bradley have been excellent stepping in for the injured Alisson, Konate and Alexander-Arnold in recent weeks but Konate could return this weekend. Klopp has Salah back which is a massive boost due to his incredible quality in...