独立的 5' 至 3' 核酸外切酶 Poly A specific 3’ to 5’ exonuclease Poly A 特异性 3' 至 5...
Exonucleases remove a single nucleotide or an oligonucleotide at the 5’ or 3’ end. Exonuclease, such as Three Prime Repair Exonuclease 1 (TREX1), plays an important role in proofreading of DNA amplification and removal of damaged DNA. Deficiency of TRE
3′-5′ exonucleases are frequently found to be associated to polymerases or helicases domains in the same enzyme or could function as autonomous entities. Here we uncovered that Candida albicans Pif1 (CaPif1) displays a 3′-5′ exonuclease activity besides its main helicase activity. These two...
Autonomous 3′→5′exonucleases are not bound covalently to DNA polymerases but are often involved in replicative complexes. Such exonucleases from rat liver, calf thymus and Escherichia coli (molecular masses of 28±2 kDa) are shown to increase more than 10-fold the accuracy of DNA polymerase...
These three exonucleases play an important role in mutation avoidance. Surprisingly, the mutation rate in an exo1 pol3-01 mutant was comparable to that in an msh2 pol3-01 mutant, suggesting that they participate directly in postreplication mismatch repair as well as in other DNA metabolic ...
化学名:3'-5' Exonuclease 1 protein antibodyCAS番号. 英語名:3'-5' Exonuclease 1 protein antibodyCBNumberCB05764842MW0MOL FileMol file3'-5' Exonuclease 1 protein antibody 生産企業 Send Inquriy ホームページ| CAS| コンピューター版Chemical Book ...
The 3 → 5 exonuclease activity of E. coli DNA polymerase III accounts for the ___ of polymerization.A.low error rateB.high speedC.directionalityD.All of the above的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题(shuashuati.com)是专业的大学职业搜题找答案
外切活性会切掉错配的碱基。没有外切活性的聚合酶容易错配，但是合成速度快
The residues forming the 3'-->5' exonuclease active site of phi 29 DNA polymerase, located at the N-terminal conserved motifs Exo I, Exo II and Exo III, have been defined by site-directed mutagenesis (Bernad, A., Blanco, L., Lázaro, J. M., Martin, G., and Salas, M. (1989) ...
Isolation and general properties of 3'-5' exonucleases I and II (EC 3.1.4.26), which are specific to single-stranded DNA, are described. Such enzymes, being components of replication complexes, could correct replication errors. Homogeneous exonucleases I and II consist of a single subunit with...