2‐deoxy‐D‐glucoseapoptosisautophagybreast cancerObjectives Compared to normal cells, malignant cells have a high degree of aerobic glycolysis, also known as the Warburg effect. Therefore, supplementing photodynamic therapy (PDT), an established cancer therapy, with metabolic inhibitors can augment the...
Here we found that a saccharide analog, 2‐deoxy‐ d ‐glucose (2‐DG), inhibits glycosylation of PD‐L1 and its immunosuppressive function by combining with EGFR inhibitor, gefitinib. Interestingly, 2‐DG/gefitinib‐induced deglycosylation of PD‐L1 decreased the expression level of PD‐L1 ...
Detection of recurrent head and neck squamous cell carcinomas after radiation therapy with 2-18F-fluoro-2-deoxy-D-glucose positron emission tomography. Laryngoscope 1999;109: 970–975 - LA, BenardFarber LA, Benard F, Machtay M, et al. Detection of recurrent head and neck squamous cell ...
2-deoxy-D-glucoseborotritide reductiontritium3H-NMRA new tritiation method was used to obtain 2-deoxy-D-glucose [2,6,61-3H] starting from a mixture of protected bromo deoxy glucose derivatives. Intermediates were characterized by 1H- and 3H-NMR....
2‐deoxy‐D‐glucoseborotritide reductiontritium3H‐NMRA new tritiation method was used to obtain 2-deoxy-D-glucose [2,6,61-3H] starting from a mixture of protected bromo deoxy glucose derivatives. Intermediates were characterized by 1H- and 3H-NMR....
Summary Previous studies have shown that 2‐deoxy‐ d ‐glucose (2‐ DG ) increases gastric motility via the vagus nerve, but the underlying mechanism remains elusive. Since nitric oxide ( NO ) is involved in gastric motility, a possible interplay between 2‐ DG and NO can be suggested. ...
Recently, positron emission tomography using 18F‐labeled fluoro‐2‐deoxy‐D‐glucose (FDG‐PET) imaging has been suggested as a sensitive and relatively more specific means to reflect tumor biologic changes after therapy. With increasingly compelling evidence, early FDG‐PET provides a reliable means...
Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models. Ann Neurol 2009;65:435-447.Stafstrom CE, Ockuly JC, Murphree L, Valley MT, Roopra A, Sutula TP. Anticonvulsant and antiepileptic actions of 2‐deoxy‐D‐glucose in epilepsy models. Ann Neurol 2009; 65(4):...
Objective: To assess the diagnostic performance of 18F‐fluoro‐2‐deoxy‐d‐glucose (18F‐FDG) positron emission tomograpy (PET)/computed tomography (CT) in nodal staging before radical cystectomy (RC) and pelvic lymph node dissection (PLND) for bladder cancer (BCa). Materials ...
Phenylboronic Acid‐Modified Near‐Infrared Region II Excitation Donor–Acceptor–Donor Molecule for 2‐Deoxy‐d‐Glucose Improved Starvation/Chemo/Photothermal Combination Therapydoi:10.1002/adhm.202302099Sun, PengfeiYang, WanHe, JiarongHe, Liuliang