Here we report that RGS14 is expressed in proximal and distal renal tubules of humans, and that RGS14 binds to NHERF1 via the PDZ2 domain. PTH inhibits NPT2A uptake of phosphate, and RGS14 blocks this action. Of
Here, we identified a novel role for one such element, regulator of G protein signaling 14 (RGS14), suggested by genome-wide association studies to associate with dysregulated Pi levels. We show that human RGS14 possesses a carboxy-terminal PDZ ligand required for sodium phosphate cotransporter ...
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简介:2024年9月18日,东京慈惠会医科大学Kenya Honda等人在Nature发表题为“Commensal consortia decolonize Enterobacteriaceae via ecological control”研究论文,研究成功从健康人类粪便样本中分离并筛选出能够强烈且特异性抑制肠道中的肠杆菌科细菌的共生细菌群落。研究者们发...
In both disorders, the retinal phenotype involves progressive rod photoreceptor loss resulting in nyctalopia and a constricted visual field, followed by subsequent cone degeneration, leading to the loss of central vision and severe visual impairment. The USH2A gene raises many challenges for researchers...
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Activin A forms a non-signaling complex with ACVR1 and type II Activin/ BMP receptors via its finger 2 tip loop. eLife. 2020;9:e54582. 40. Gilboa L, Wells RG, Lodish HF, Henis YI. Oligomeric structure of type I and type II TGF-b receptors: homo-dimers form in the ER and persist...
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32 版权 © 2010–2018, Texas Instruments Incorporated www.ti.com PACKAGE OPTION ADDENDUM 14-May-2025 PACKAGING INFORMATION Orderable part number Status Material type (1) (2) Package | Pins Package qty | Carrier TPS51916RUKR TPS51916RUKR.Z TPS51916RUKRG4.Z TPS51916RUKT TPS51916RUKT.Z ...
ILIM DIAG_EN FLT SNS Voltage Scaling Gate Driver / Reverse FET Turnon Diagnostics and Protection Sensing CFILTER RSNS RILIM RGND GND Power FET x4 Current Limit Thermal Shutdown Current Sense Fault Indication VOUTx 4 CVOUT 代表的なアプリケーション回路図 このリソースの元の言語は英語です....