Vitamin D 25-hydroxylase deficiency. Mol Genet Metab 2004 ; 83:197 - 8; http://dx.doi.org/ 10.1016/j.ymgme.2004.07.006 ; PMID: 15464435Dong Q, Miller WL. 2004. Vitamin D 25-hydroxylase deficiency . Mol Genet Metab 83 :197–198...
(20.61±4.70)ng/mL,P <0.01],andthedeficiencyrateof100.0% (30/30)wassignificantlyhigherthan 54.0% (27/50).Moreover,theserumlevelof25-(OH)Dintherecoveryperiod(3 monthslater)wassignificant- lyhigher[(10.14±2.92)ng/mLvs (15.94±4.88)ng/mL,P <0.01],andthedeficiencyratewassignificantly decreased...
Cholesterol 25-hydroxylase (CH25H) is an enzyme that catalyses the oxidation of cholesterol to form the soluble product 25-hydroxycholesterol (25-HC). 25-HC is an oxysterol that can play an important role in different biological processes7,8. Studies of 25-HC have identified it as an innate...
Obesity represses CYP2R1, the vitamin D 25‐hydroxylase, in the liver and extrahepatic tissuesvitamin Dobesityhigh‐fat dietCYP2R125‐hydroxyvitamin DCYP27B1VDRCYP24A1Low plasma level of 25﹉ydroxyvitamin D (25㎡H〥), namely vitamin D deficiency, is associated with obesity and weight loss ...
ConclusionVitamin D deficiency is a common problem in newly diagnosed T2DM, especially in KPDM. Low serum 25OHD level seems to be an independent risk factor for ketosis-prone in patients with newly diagnosed T2DM. KEYWORDS: Diabetes mellitus, type 2;Ketosis-prone diabetes;Vitamin D Corresponding...
One of the vitamin D responsive genes, 25(OH)D3-24- hydroxylase (cytochrome P450 family 24 subfamily A member 1) mRNA expression is up-regulated by 25(OH)D3 at 250–500 nM and by 1α,25-(OH)2D3 at 1–10 nM. 25(OH)D3 and 1α,25-(OH)2D3 at a time-dependent manner ...
Logistic回归分析血清25(OH)D水平与Meige综合征的相关性。 结果Meige综合征患者血清25(OH)D浓度为(12.68±6.77) μg/L,明显低于健康对照组(17.93±6.93) μg/L,差异有统计学意义( t=4.044, P<0.001)。Meige综合征患者Ⅰ、Ⅱ、Ⅲ亚型血清25(OH)D浓度分别为(14.7±8.14 )、(11.4±5.02)、(8.38±4.99) μ...
The 5-HT deficiency theory of depression : 示观察组HAMD评分与血清25 (OH )D3水平呈负 perspectives from a naturalistic 5-HT deficiency r P model ,the tryptophan hydroxylase 2Arg493His 相关( =-0.97 , 0.01 ),与上述结论相同。 knockin mouse[J]. Philos Trans R Soc Lond B Biol 综上所述,...
Vitamin D regulates tyrosine hydroxylase expression: N-cadherin a possible mediator[J]. Neuroscience, 2015,304:90-100. DOI: 10.1016/j.neuroscience.2015.07.048 . 返回引文位置Google Scholar 百度学术 万方数据 [22] Pertile RA , Cui X , Eyles DW . Vitamin D signaling and the differentiation of...
hydroxylase Liver microsomal vit D-25-hydroxylase Renal 25(OH)D-1-hydroxylase Tissue (non-renal) 25(OH)D-1-hydroxylase Renal Mitochondrial 25(OH)D-24-hydroxylase Non-renal 1,25 (OH)2D- 24-hydroxylase An “unregulated” step in flow of metabolism A regulated step in the flow of metabolism...