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computation Article Designing of Parking Spaces on Parking Taking into Account the Parameters of Design Vehicles Miroslava Mikusova 1,* , Jamshid Abdunazarov 2, Joanna Zukowska 3 and Juraj Jagelcak 1 1 Faculty of Operation and Economics of Transport and Communications, Department of Road and Urban...
近日,百济神州宣布在一项评估其在研PD-1抗体tislelizumab (BGB-A317)作为晚期不可切除或转移性食道鳞状细胞癌(ESCC)患者的潜在二线治疗的全球3期临床试验中实现了首例患者给药。此外,tislelizumab用于非小细胞肺癌和肝细胞癌患者的...
我们的一项研究[2](BGB-A317-2001-IIT研究)显示,对于EGFR-TKIs耐药、且耐药机制不明、无其他成药靶点、能耐受的患者,非铂方案(单药化疗+贝伐珠单抗+PD1抑制剂)是个不错的选择,可以取得很好的疗效。 除了在对靶向治疗耐药的肺癌患者的治疗方面...
Resistance to quinolones was mediated by the presence of four copies of the oqxBgb and qepA genes in the five isolates, while the catB7 gene was responsible for the phenicol resistance, and sulI, tetA, tcr-3, and tetR were responsible for the resistance to sulfonamides and tetracyclines, ...
纯度规格: 99.74% 产品类别: 抑制剂 货号: T7584 Product Introduction Bioactivity 名称 zanubrutinib 描述 Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK). 体外活性 在生化和细胞实验中,zanubrutinib展现出了nM级的BTK抑制活性。在多条MCL和DLBCL细胞系中,zanubrutinib抑制了...
另一项BGB-3111-AU-003试验(NCT02343120)纳入的既往经治的MZL患者(n = 20)中,45%的患者患有结外MZL,25%的患者患有淋巴结MZL,30%的患者患有脾脏MZL。患者接受百悦泽®治疗的每日用药总剂量为320 mg/天,包括每次服用160 mg、每日两次,或每次服用320 mg、每日一次。
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