In enzymology, a 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) is an enzyme that catalyzes the chemical reaction. (R)-glycerate + NAD(P)+ightleftharpoons 2-hydroxy-3-oxopropanoate + NAD(P)H + H+. The 3 substrates of this enzyme are (R)-glycerate, NAD+, and NADP+, whereas ...