and audited 306 packages in 2m 57 packages are looking for funding run `npm fund` for details 2 vulnerabilities (1 moderate, 1 high) To address all issues (including breaking changes), run: npm audit fix --force Run `npm audit` for details. npm notice npm notice New patch version of ...
Figure 1.GradingthecertaintyofevidenceandstrengthofrecommendationsinACPclinicalguidelinesusingGRADE. Grading Certainty of Evidence High Confident that the true effect lies close to the estimate of the effect (the intervention “results in” the effect). Moderate Moderately confident in the effect estimate:...
While we are working on Nuxt 3 stable release, Nuxt 2 has to keep some dependencies in their older versions to avoid breaking changes. These include webpack@4, postcss@7 and core-js@2. (Update: You can now migrate to nuxt bridge: https:/...
Though variants of ACE2 have been engineered to increase their affinity to spike (and thus their neutralization potency) [49], optimized residues may introduce new vulnerabilities to escape. Alternatively, host-directed antibodies targeting ACE2 have circumvented this limitation and shown in vivo ...
(2004). Adolescent brain de- velopment: A period of vulnerabilities and oppor- tunities. Keynote address. In Ronald E. Dahl & Linda Patia Spear (Eds.), Adolescent brain develop- ment: Vulnerabilities and opportunities (Vol. 1021, pp. 1–22). New York, NY: New York Academy of Sciences...
3.1. GAS2 Is Significantly Upregulated in Persistent BCR::ABL1+ LSCs after TKI Treatment To study potential vulnerabilities in the persistent LSC population, we used the publicly available dataset GSE76312 [6], which comprises single-cell RNA seq data from 27 CML patients at diagnosis and after...
Moderate Confidence: Judgments are based on information that is credibly sourced and plausible, but not of sufficient quantity or corroborated sufficiently to warrant a higher level of confidence. This level of confidence is used to express that judgments carry an increased probability of being incorrec...
The COVID-19 pandemic has put healthcare infrastructures and our social and economic lives under unprecedented strain. Effective solutions are needed to end the pandemic while significantly lessening its further impact on mortality and social and economi
Sparked by media reports of severe COVID-19 outcomes in children where a high IQ was indicated, we investigated further evidence for potential SARS-CoV-2 vulnerabilities in paediatric (age 19 years or younger) patients with a high IQ by conducting a search of the National Center for Biotechnolo...
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