2-Oxoglutarate-dependent dioxygenases (2OGDDs) are a superfamily of enzymes that play diverse roles in many biological processes, including regulation of hypoxia-inducible factor-mediated adaptation to hypoxia, extracellular matrix formation, epigenetic regulation of gene transcription and the reprogramming ...
2-Oxoglutarate-dependent dioxygenases (2OGDDs) are conserved and common dioxygenases whose activities depend on O2, Fe2+, and 2OG. Most 2OGDDs are expressed in the brain and are essential for the development and functions of the brain. Therefore, 2OGDDs likely play essential roles in ...
2-Oxoglutarate-dependent dioxygenases (2-ODDs) catalyze numerous steps in biosynthetic pathways of plants. Prohexadione-Ca is a known inhibitor of such rea... H Halbwirth,TC Fischer,K Schlangen,... - 《Plant Science》 被引量: 58发表: 2006年 2-Oxoglutarate-dependent dioxygenases in plants: ...
The 2-oxoglutarate-dependent dioxygenase (2OGD) superfamily is the second largest enzyme family in the plant genome, and its members are involved in various oxygenation/hydroxylation reactions. Despite their biochemical significance in metabolism, a systematic analysis of plant 2OGDs remains to be acc...
This review discusses recent advances in the biochemistry and molecular biology of dioxygenases occurring in different biological systems.关键词: 2-Oxoglutarate-dependent dioxygenase dioxygenase-related function mammalian microbial plant purification characterization kinetic parameters ...
L-2-Hydroxyglutaric acid is potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs) including the Ten Eleven Translocation (TET) enzymes. S-2-羟基戊二酸上下游产品信息上游原料下游产品S-2-羟基戊二酸 试剂级价格 更新日期:2024/11/08 产品编号:HY-W015114 产品名称:L-2-Hydroxy...
体外研究 L-2-Hydroxyglutaric acid is potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs) including the Ten Eleven Translocation (TET) enzymes. S-2-羟基戊二酸 - 简介 S-2-羟基戊二酸(S-2-Hydroxybutanedioic acid)也称为L-乳酸(Lactic acid),是一种有机酸。它具有无色至...
英文名称:s-2-Hydroxypentanedioic acid disodium salt CAS:63512-50-5 纯度:95+% 备注:A6312 山东西亚化学有限公司 联系电话: 4009903999 13355009207 产品介绍: 中文名称:S-2-羟基戊二酸;S-2-羟基戊二酸 CAS:63512-50-5 纯度:>=98.0% (GC)
4.3 2-Oxoglutarate (2OG; α-Ketoglutarate) The 2OG is crucial in nitrogen metabolism, and also is important for epigenetic regulations. The 2OG is the cosubstrate of 2OG-dependent dioxygenases (2OGDD) that are involved in histone and DNA regulation, thus regulating genome expression in mammal...
Here, by differential transcriptome mining, we identified six 2-oxoglutarate-dependent dioxygenase (2-ODD) genes whose expressions corresponded to tanshinone biosynthesis. We showed that Sm2-ODD14 acts as a dehydrogenase catalyzing the furan ring aromatization. In vitro Sm2-ODD14 converted ...