2-oxocarboxylic acid metabolism 2-oxocarboxylic acids, also called 2-oxo acids and alpha-keto acids, are the most elementary set of metabolites that includes pyruvate (2-oxopropanoate), 2-oxobutanoate, oxaloacetate (2-oxosuccinate) and 2-oxoglutarate. this diagram illustrates the architecture of ...
S3a–c and Table S3). For example, the SARS-CoV-2 vRNA interactome was specifically enriched for host factors with annotated functions in the TCA cycle and the 2-Oxocarboxylic acid metabolism (FDR < 0.05); both of these metabolic pathways are known to be disrupted upon SARS-CoV-2 in...
A series of new 3-tropanol and 3-quinuclidinol esters of phenyl-substituted pyrrolidin-, piperidin- and azepin-2-oxocarboxylic acid were synthesized and tested for antimuscarinic activity. The compounds showed a preferential in vitro activity at M-1 and M-3 receptor subtypes and an interesting...
This new process which employs the hydrazone method allows the efficient synthesis of enantiomerically pure, benzyloxymethyl(BOM)-protected 4-hydroxy-2-oxocarboxylic acid esters (R)- and (S)-2.doi:10.1002/anie.199304211Prof.InstitutDr.Institut...
Several metabolism-related pathways including 2-oxocarboxylic acid metabolism, citrate cycle (TCA cycle), and lipoic acid metabolism (Fig. S8D), indicated that RAD54L may affect ccRCC progression via the above pathways. Collectively, these findings suggest that RAD54L had an oncogenic role in ccRCC...
2-Ketoglutaric acid is a 2-oxocarboxylic acid (2-OCA), one of the important intermediates in the Krebs cycle, after isocitrate and before succinyl CoA. It is an important nitrogen transporter and is transaminate along with glutamine to form glutamate. It can be used to differentiate microorganis...
00983Drug metabolism - other enzymes Reaction module maps 012102-Oxocarboxylic acid metabolism 01220Degradation of aromatic compounds Chemical structure transformation maps 01010Overview of biosynthetic pathways 01060Biosynthesis of plant secondary metabolites 01061Biosynthesis ofphenylpropanoids 01062Biosynthesis ofterpe...
Acetyl-CoA serves as a central hub involved in the supply of energy and redox power.In addition to the rearrangement of protein synthesis, pronounced changes were observed in fatty acid metabolism. The13C labelling pattern of acetate in the tracer experiment indicated a strong incorporation of biom...
Acetyl-CoA serves as a central hub involved in the supply of energy and redox power.In addition to the rearrangement of protein synthesis, pronounced changes were observed in fatty acid metabolism. The13C labelling pattern of acetate in the tracer experiment indicated a strong incorporation of biom...
hsa01200 Carbon metabolism - Homo sapiens (human) hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human) hsa01212 Fatty acid metabolism - Homo sapiens (human) hsa01230 Biosynthesis of amino acids - Homo sapiens (human) ... 第三种形式是 brite 层次结构的类似选项:https://rest.kegg.jp...