3,5-Dichloro-4-methylpyridine (500 mg, 1 eq.) is dissolved in dry THF (2 mL) under nitrogen atmosphere at −60° C. LiN(TMS)2 (1.0M in THF, 3.38 mL, 1.1 eq.) is added dropwise via syringe, keeping the temperature below −55° C. The mixture turns yellow and is stirred at...
Acido 1 - (1 - (2-etoxidil) - 3-ethyl-7 - (4-methylpyridine-2-pyridine-7) - 1h-pyrazol [4,3-d] pyridine-5-il) pyridine-4-carboxilic and its saltsAbout 1 - (1 - (2-etoxidil) - 3-ethyl-7 - (4-methylpiridin-2-ilamin) - 1 h-pirazolo [4, 3-d] pirimidin-5-il) ...
Method 1: 4-methylpyridine is dissolved in anhydrous diethyl ether, under protection of nitrogen, a solution of phenyl lithium in diethyl ether is added dropwise with stirring at room temperature, the reaction is continued. Nitrogen is stopped, cool to 0 ℃, ethyl acetate is added dropwise at ...
3-Cyano-2-hydroxy-6-methylpyridine 3-氰基-6-甲基-2(1H)-吡啶酮性质、用途与生产工艺 简介 3-氰基-6-甲基-2(1H)-吡啶酮是米力农(Milirinone)的中间体。米力农系1,6-二氢-2-甲基-6-氧代-[3,4'二吡啶]-5-甲腈的通用名。米力农是磷酸二酯酶III(PDEIII)抑制剂,于1987年美国上市的第二代双吡啶类...
英文名称3-Bromo-4-methylpyridine 储存温度避光 运输条件常规运输 产品介绍 3-Bromo-4-methylpyridine may be used as a building block in the preparation of: · substituted 4-(2,2-diphenylethyl)pyridine-N-oxides for use as potent phosphodiesterase type 4 (PDE4) inhibitors ...
2-Bromo-6-methoxy-4-methylpyridine 2-溴-6-甲氧基-4-甲基吡啶 1256807-52-9 3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylic acid 3-氨基-4,6-二甲基噻吩并[2,3-b]吡啶-2-羧酸 58327-76-7 4-Bromo-3-fluoroanisole 4-溴-3-氟苯甲醚 458-50-4 Methyl 3,5-dihydroxybenzoate 3,...
Preparation of 2-(3-(ieri-butoxycarbonyl)phenyI)-3-methylpyridine-l-oxide. u [00200] tert-Butyl-3-(3-methylpyridin-2-yl)benzoate (1.0 eq) was dissolved in EtOAc (6 vol). Water (0. 3 vol) was added, followed by urea-hydrogen peroxide (3 eq). Phthalic anhydride (3 eq) was the...
pentanone-->4-Methylpyridine-->4-Pyridyl acetone-->Phenyllithium-->Malononitrile-->Sodium Methoxide-->4-(dimethylamino)-3-(4-pyridyl)-3-buten-2-one-->2-cyano-3-ethoxyacrylamide-->2-cyano-3-(dimethylamino)prop-2-enamide-->5-Bromo-3-cyano-2-hydroxy-6-methylpyridine-->Ethoxymethylene...
2-Bromo-3-hydroxy-6-methylpyridine. Acta Cryst. 2013, 69, 1–6. [CrossRef] 43. Hobza, P.; Zahradnik, R. Intermolecular Complexes; Elsevier: Amsterdam, The Netherlands, 1988. 44. van Duijneveldt, F.B.; van Duijneveldt-van de Rijdt, J.G.C.M.; van Lenthe, J.H. State of the...
Synthesis of [Cu(L1)2(NO3)2] L1 = 2-Bromo-5-methylpyridine A total of 0.241 g (1 mmol) of Cu(NO3)2·3H2O was dissolved in 3 mL of MeCN and added to 3 mL of MeCN solution containing 0.170 g (1 mmol) 2-bromo-5-methylpyridine. The mixture was stirred for 3 h and then a ...