et al. Evaluating the applicability of mouse SINEs as an alternative normalization approach for RT-qPCR in brain tissue of the APP23 model for Alzheimer’s disease. J. Neurosci. Methods 320, 128–137 (2019). Article CAS PubMed Google Scholar Trypsteen, W. et al. ddpcRquant: threshold ...
[52] Imaging and Spectral Characteristics of Amyloid Plaque Autofluorescence in Brain Slices from the APP/PS1 Mouse Model of Alzheimer's Disease 2019,《Neuroscience Bulletin》,IF:4.326 [53] Rostral and Caudal Ventral Tegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate in Opi...
https://doi.org/10.1093/plcell/koae039 3.施一公团队发现FAD机制 简介:2024年2月12日,堪萨斯大学Michael S. Wolfe及清华大学/西湖大学施一公等多团队合作在Cell Reports在线发表题为“Familial Alzheimer mutations stabilize synaptotoxicγ-secretase-substrate complexe...
Microglia, the resident immune cells of the brain, regulate neuroinflammation which can lead to secondary neuronal damage and cognitive impairment under pathological conditions. Two of the many molecules that can elicit an inflammatory response from microglia are lipopolysaccharide (LPS), a component of ...
etc. One of them, galanthamine, is a worldwide registered drug for the treatment of cognitive decline in mild to moderate Alzheimer’s disease and various other memory impairments [3,4]. To date, over 600 Amaryllidaceae alkaloids have been reported up to the end of 2018, and the number is...
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The Thiadiazolylpiperazine Compounds can be used to treat or prevent a cognitive disorder, including but not limited to, delirium and dementia such as multi-infarct dementia, dementia pugilistica, dementia caused by AIDS, and dementia caused by Alzheimer's disease. The Thiadiazolylpiperazine Compound...
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem 2009;109:153-9.X. Wang, B. Su, L. Zheng, et al., The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease, J. Neurochem. 109 (2009) 153e159....