tert-butyl-[[(2R,3S,5R)-3-[tert-butyl(dimethyl)silyl]oxy-5-(2,6-dimethyl-3-pyridinyl)-2-oxolanyl]methoxy]-dimethylsilane 1446906-38-2 C24H45NO3Si2 trans-2,2'-bipyridinium tungsten bis(pyridine) tetrabromide 147040-39-9 C20H19Br4N4W tri(propan-2-yl)-[2-[4-[19-[4-[2-tri...
N-[3-[4,4-dimethyl-6-(trifluoromethyl)-2,3-dihydro-1H-quinolin-2-yl]phenyl]-3-pyridinesulfonamide 1373545-64-2 C23H22F3N3O2S N-(7-chloro-4-quinolinyl)-N',N'-bis[2-(diethylamino)ethyl]ethane-1,2-diamine 1192250-33-1 C23H38ClN5 N-butyl-N-methyl-N'-sulfanilyl-urea|N-Butyl-...
6-Dichlorobenzonitrile 2,3-Dicyano-1,4- dithiaanthraquinone Isoprothiolane 167 17109-49-8 乙基二苯二硫代磷酸脂 Ethyldiphenyl dithiophosphate 168 640-15-3 二甲硫吸磷 Thiometon 169 35400-43-2 o-乙基-o-4-甲基苯硫基-S-丙基二 o-Ethyl-o-4-methylthiophenyl-S- 硫代磷酸脂 propyl ...
N-(3-azetidinyl)-6-(6-methoxy-3-imidazo[1,2-a]pyridinyl)-2-pyridinamine 1044733-40-5 C16H17N5O N-(4-acetamido-2-nitrophenyl)glycine ethyl ester 117131-27-8 C12H15N3O5 N-(2-chlorophenyl)-4-[5-methyl-2-(4-methylsulfonylphenyl)-3-pyrazolyl]-1-piperidinecarboxamide 1470190-27-2 ...
As shown in Scheme 16, a substituted pyrazole compound containing a sulfone or sulfoxide functionality as in 16-6 can be prepared by a variety of methods, such as starting with an appropriately substituted bromo thiophenyl ether 16-2. Thioether 16-2 may be readily prepared by alkylation of th...
yl]oxy}pyridine-3-carboxylate; methyl 4-cyano-2-{[(3R,6R)-1-{[6-methoxy-2-(2H-1,2,3-triazol-2-yl)pyridin-3-yl]carbonyl}-6-methylpiperidin-3-yl]oxy}pyridine-3-carboxylate; methyl 4-cyano-2-{[(3R,6R)-1-{[3-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl]carbonyl}-6-methyl...
6-[(2R,5S)-7-methyl-6-oxo-1,7-diazaspiro[4.4]nonan-2-yl]-4-pyridyl]-4-(trifluoromethyl)benzamide hydrochloride; 2-[2-methyl-6-[(2S,5S)-7-methyl-6-oxo-1,7-diazaspiro[4.4]nonan-2-yl]-4-pyridyl]-4-(trifluoromethyl)benzamide hydrochloride; 2-[2-methyl-6-[(2R,5R)-7-methyl-6...
[2,3-b]pyridinyl, benzothiophenyl, 1,5-naphthyridinyl, furo[3,2-b]pyridine, [f,2,4jtriazolo[1,5-alpyridinyl, benzo [1,2,3]triazolyl, imidazo[1,2-a]pyrimidinyl, [i,2,4]triazolo[4,3˜b]pyridazinyl, benzo[c][1,2,5] thiadiazolyl, benzo[c][1,2,5]oxadiazole, 1,3-...
1. A compound having the formula: or a pharmaceutically acceptable salt thereof wherein R1 is —H; R2 is —H; Q is a 6 membered heteroaryl ring selected from pyridyl, pyrimidyl, pyrazinyl, triazinyl or pyridazinyl optionally substituted with 1-3 JQ groups; or the compound has the formula...
WO/2006/115452 November, 2006 USE OF PYRAZOLYL-PYRIMIDINE DERIVATIVES IN THE TREATMENT OF PAIN WO/2006/123113 November, 2006 PYRAZOLYLAMINOPYRIMIDINE DERIVATIVES USEFUL AS TYROSINE KINASE INHIBITORS WO/2007/049041 May, 2007 4- (3-AMINOPYRAZOLE) PYRIMIDINE DERIVATIVES FOR USE AS TYROSINE KINASE INHIBIT...