2,3-BPG支路(2,3-BPGalternative pathway) 2,3-BPG支路(2,3-BPGalternative pathway) 查看答案
红细胞糖酵解过程中形成的侧支循环,即红细胞糖酵解途径中产生的1,3-BPG可转变成中间产物2,3-BPG,后者再转变成甘油酸-3-磷酸而返回糖酵解的过程。 英文名称 2,3-bisphosphoglyceric acid shunt pathway; 2,3-biphosphoglycerate shunt pathway; 2,3-BPG shunt pathway ...
B、The contents of 2,3-BPG are high in red blood cells. C、2,3-BPG in erythrocytes lower hemoglobin affinity for oxygen. D、In the same PO2, O2 released by Hb increases with the increase of 2,3-BPG concentration.暂无答案更多“The false statement about the 2, 3-BPG shunt pathway is...
Rapoport-luebering pathway A third metabolic shunt generates 2,3-bisphosphoglycerate (2,3-BPG; also called 2,3-diphosphoglycerate or 2,3-DPG). 1,3-BPG is diverted bybisphosphoglycerate mutaseto form 2,3-BPG (Figure 6.1). 2,3-BPG binds between the globin chains in the interior cavity of...
在培养条件上,摸索到合适的葡萄糖浓度为10g/L,合适的诱导时间为4 h,并发现在诱导时加入终浓度0.5%的Tween 80可以促进2,3-BPG穿过大肠杆菌细胞壁分泌入培养基。为接下来的回收纯化工作打下了良好的基础。 参考文献 [1]Metabolic pathway analysis of enzyme-deficient human red blood cells[J].BioSystems.2004(1...
(8)甘油酸-2-磷酸的生成78页Formation of 2-Phosphoglycerate 中间产物是:2,3- 二磷酸甘油酸(BPG)(9)磷酸烯醇式丙酮酸的生成Formation of Phosphoenolpyruvate(10)丙酮酸的生成Formation of Pyruvate & ATP 是此途径的第三个调节酶(共价修饰调节和变构调节,A、M、L型)。ATP、长链脂肪酸、乙酰CoA丙氨酸有抑制...
2,3-BPG旁路的主要生理功能是调节血红蛋白(Hb)运氧 2,3-BPG是一个负电性较高的分子,可与血红蛋白结合,结合部位在Hb分子4个亚基的对称中心孔穴内。2,3-BPG的负电荷基团与组成孔穴侧壁的2个β亚基的带正电荷基团形成盐键,从而使Hb分子的T构象更趋稳定,降低与O2的亲和力。 当血液通过氧分压较高的肺部时,2...
内容提示: 2,3-bisphosphoglycerate 3-phosphatase 3.1.3.801 NomenclatureEC number3.1.3.80Systematic name2,3-bisphospho-d-glycerate 3-phosphohydrolaseRecommended name2,3-bisphosphoglycerate 3-phosphataseSynonyms2,3-BPG 3-phosphataseDdMipp1 <3> [1]HsMIPP1 protein <2> [1]MIPP1 protein <1> [1]2 ...
糖代谢3-2 第六章 糖代谢-part3 MetabolismofCarbohydrates 目录 第五节 糖原的合成与分解 GlycogenesisandGlycogenolysis 目录 糖原的定义：糖原(glycogen)是动物体内糖的储存形式 之一，是机体能迅速动用的能量储备。糖原储存的主要器官及其生理意义：肌肉：肌糖原，180~300g，主要供肌肉收缩所需 肝脏：肝...
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) is an NAD+-dependent oxidoreductase that converts glyceraldehyde 3-phosphate (GAP) to 1,3-bisphosphoglycerate (1,3-BPG) in the sixth step of glycolysis with an inorganic phosphate as a cofactor. Early studies defined GAPDH as a 1...