红细胞2,3-二磷酸甘油酸合成酶 2,3-二磷酸甘油酸(2,3-BPG,2,3-Bisphosphoglycerate)是生命体内糖酵解途径的中间产物1,3-二磷酸甘油酸(1,3-BPG,1,3-Bisphosphoglycerate)的同分异构体,由仅存在于血红细胞和胎盘中的酶——二磷酸甘油酸变位酶(BPGM,Bisphosphoglycerate mutase,旧称DPGM,diphosphoglycerate mu...
However, what triggers its induction at high altitude is unknown. To address this question, we recruited 24 individuals and placed them at high altitude for different time points. Here we report that 1) Plasma adenosine and erythrocyte 2,3-BPG levels were significantly elevated in normal ...
10% more oxygen at a given PO2in the presence of 2,3-DPG than it does in its absence (Figure 2). Synthesis of 2,3-DPG is increased at high altitude when respiratory alkalosis stimulates glycolysis (the glycolytic enzyme phosphofructokinase has a high optimum pH). A rightward shift in ...
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The probe may be used to develop a new generation of 2,3-BPG detection kit applicable for diseases like hypoxia, high altitude pulmonary edema, hyperthyroidism, congestive heart failure, etc. More information can be found in the Communication by Prithidipa Sahoo etal. on page71 in Issue1, ...