18F-FE-PE2Idoi:10.1007/978-3-031-10271-4_50FE-PE2I is used for assessment of dopamine transporter function in the striatum of the brain in evaluation of Parkinsonian symptoms.Ballinger, James R.King’s College London
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The main objective of this work was to validate this correction approach in human data for 18F-FE-PE2I, a tracer which measures the dopamine transporter availability.Praveen HonharDavid MatuskeyRichard CarsonAnsel HillmerJournal of Nuclear Medicine...
The dopamine transporter (DaT) PET ligand [18F]FE-PE2I is used to aid the diagnosis of Parkinson's disease. After encountering four patients with a history of daily sertraline use, who all showed atypical findings on [18F]FE-PE2I PET, we suspected that the selective serotonin reuptake ...
In addition, due to the high extraction of [18F]FE-PE2I from blood, the early part of the scan can also provide information about brain perfusion. Here we report intermediate findings about DAT availability and perfusion alterations from an ongoing [18F]FE-PE2I PET study in patients with ...
18F-FE-PE2I is a suitable PET radioligand for DAT quantification and imaging with good pharmacokinetics. The aim of this study was to determine a clinical optimal simplified reference tissue-based image acquisition protocol and to compare the discriminatory value and effec...
While the excellent discriminative power of [18F]FE-PE2I PET has been established, so far only one study has reported meaningful associations between motor severity scores and DAT availability. In this study, we use high-resolution (3 mm isotropic) PET to provide ...
In vitro autoradiography and in vivo evalua- tion in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand. Synapse 2009; 63: 871-880.Varrone A, Steiger C, Schou M et al (2009) In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18 F]FE-...
In vivo activity of modafinil on dopamine transporter measured with positron emission tomog- raphy and [18F]FE-PE2I. Int J Neuropsychopharmacol. 2014;17(5): 697-703.Kim W, Tateno A, Arakawa R, Sakayori T, Ikeda Y, Suzuki H, Okubo Y. In vivo activity of modafinil on dopamine ...
Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I. J. Nucl. Med. 52, 132-139.Varrone A, Toth M, Steiger C, et al. Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with...