In this case, the ED to humans upon an iv application of ~300 MBq [18F]FACH would be about 6.2 mSv. This risk assessment encourages the translation of [18F]FACH into clinical study phases and the further investigation of its potential as a clinical tool for cancer imaging with PET....
Pharmaceuticals, Vol. 11, Pages 30: Comparison Study of Two Differently Clicked 18F-Folates—Lipophilicity Plays a Key RolePharmaceuticals doi: 10.3390/ph11010030Authors:Kathrin Kettenba ...KettenbachKathrinReffertLaura MSchiefersteinHannoPektorStef...
One-step radiosynthesis of the MCTs imaging agent [18F]FACH by aliphatic 18F-labelling of a methylsulfonate precursor containing an unprotected carboxylic acid groupNuclear chemistryAnalytical chemistryThe potent MCT1 inhibitor as lead compound and its corresponding fluorinated analogue FACH on the basis ...
Pharmaceuticals, Vol. 10, Pages 99: Convenient Preparation of 18F-Labeled Peptide Probes for Potential Claudin-4 PET ImagingPharmaceuticals doi: 10.3390/ph10040099Authors:Lucia FeniM ...LuciaOmraneM. AymenFischerMoritzZlatopolskiyBoris DNeumaier...