RGD, 18F-Galacto-RGDdoi:10.1007/978-3-642-16483-5_5091The selection of patients considered for antiangiogenic therapy may benefit from specific biomarkers defining individual angiogenetic activity in tumor tissue. Integrinsare heterodimeric...Springer Berlin Heidelberg...
精氨酸一甘氨酸一天冬氨酸(Arg-Gly-Asp,RGD)肽可特异性地与整合素avB。受体结合,”F标记的RGD肽 类化合物PET显像可无创、动态地定量监测整合素avB3受体表达,在肿瘤早期诊断、疗效监测及抗血管新 生评价上发挥着重要作用。本文就近年来国内外F标记RGD肽在肿瘤av&受体显像中的研究进展作简 ...
18)F-Galacto-RGD is a new tracer for PET imaging of alpha v beta3, a receptor involved in a variety of pathologic processes including angiogenesis and metastasis. Our aim was to study the dosimetry of (18)F-galacto-RGD in humans. Eighteen patients with various tumors (musculoskeletal tumors...
(18)F-Galacto-arginine-glycine-aspartic acid (RGD) has been developed for positron emission tomography (PET) imaging of integrin alpha(v)b... TCPD Frederick 被引量: 143发表: 2009年 18F-Labeled Galacto and PEGylated RGD Dimers for PET Imaging of αvβ3 Integrin Expression Watzlowik P, ...
Imaging of integrin alpha(v)beta(3) expression in patients with malignant glioma by [18F] galacto-RGD positron emission tomography. Neuro Oncol 2009;11:861-70. Article PubMed Central PubMed Google Scholar Hoshiga M, Alpers CE, Smith LL, Giachelli CM, Schwartz SM. Alpha-v beta-3 ...
Nodaga-rgd Nodaga-theranost Galacto-RGD NOTA-cyclic RGDyK [18F]FB-RGD NOTA-P2-RM26 (68Ga)Nota-prgd2 NOTA-WL12 Dota-ggga cyclic Arg(Pbf)-Gly-Asp(Ot-Bu)-D-Tyr(Ot-Bu)-Lys(NH2) Cyclo(-RGDfK) cyclic( RGDyK) Azido cyclic(RGDyK) ...
Noninvasive imaging of alpha(v)beta3 integrin expression using 18 F-labeled RGD-containing glycopeptide and positron emission tomography. Cancer Res. 2001;61(5):1781–5. CAS PubMed Google Scholar Haubner R, Kuhnast B, Mang C, Weber WA, Kessler H, Wester HJ, et al. [18 F]Galacto-RGD...
[18F]Galacto-RGD: Synthesis, Radiolabeling, Metabolic Stability, and Radiation Dose Estimates It has been demonstrated in various murine tumor models that radiolabeled RGD-peptides can be used for noninvasive determination of 伪v尾3 integrin express... R Haubner,B Kuhnast,C Mang,... - 《Bi...
结论:99mTc-Galacto-RGD2是一种很有临床价值的整合素受体显像剂.SPECT/CT断层显像对于重叠病灶有很好的检出率.在SPECT/CT的定量中得到的SUV max与PET/CT的SUV max有很好的相关性,所以SPECT/CT的SUV max在一定意义上可以对肺癌进行定量描述.SPECT/CT临床应用广泛,费用低,SPECT/CT定量技术还有巨大的潜力有待开发,...
Imaging of delayed-type hypersensitivity reaction by PET and 18F-galacto-RGD. J Nucl Med 2005;46:184-189.Pichler BJ, Kneilling M, Haubner R, et al. Imaging of delayed-type hypersensi- tivity reaction by PET and 18F-galacto-RGD. J Nucl Med. 2005;46:184-189....