PP-F11N LUTETIUM LU-177,来源于药化词典-药智数据
Novel minigastrins (NMGs) as analogs of PP-F11N with one or two amide bonds substituted by 1,2,3-triazoles were synthesized, radiolabeled with 177Lu3+, and subjected to full evaluation in vitro (cell internalization, receptor affinity, stability in blood plasma) and in vivo (stability, ...
药物别名 Lutetium lu 177 pp-f11n 扩展信息 专利信息 VIP试用医疗器械查询APP下载客服中心常见问题数据可视化数据分析挖掘系统网站地图业务介绍友情链接 400-678-0778 投诉热线: (023) 6262 8397 邮箱: tousu@yaozh.com QQ: 236960938 友情链接: 药物在线 药品注册查询 临床试验查询 参比制剂目录...
The aim of this prospective clinical study is to test the proof of principle that the novel gastrin analogue [177Lu-DOTA-(DGlu)6-Ala-Tyr-Gly-Trp-Nleu-Asp-PheNH2] (177Lu-PP-F11N) targets effectively metastases of MTC (ClinicalTrials.gov: NCT02088645). Methods: Six patients received two...
Lu-177-DOTA-PP-F11N had the same biodistribution as Lu-177-DOTA-PP-F11; however, uptake in the MZ-CRC-1 tumors was almost double (20.7 +/- 1.71 vs. 11.2 +/- 2.94 % IA [percentage injected activity]/g, P < 0.0002). Coadministration of phosphoramidon or thiorphan increases Lu-177-...