Exaggerated 17-hydroxiprogesterone response to short-term adrenal stimulation and evi- dence for CYP21B gene point mutations in true preco- cious puberty. Clin Endocrinol (Oxf) 1998;48:555-60.Cisternino M,Dondi E,Martinetti M,et al.Exaggerated 17-hydroxyprogesterone response to short-term adrenal...
目的探讨17-羟孕酮(17-OH-progesterone,17-OHP)、促肾上腺皮质激素(adrenocorticotropic hormone,ACTH)联合血清睾酮在先天性肾上腺皮质增生症(congenital adrenal hyperplasia,CAH)新生儿早期筛查中的应用价值。 方法选定郑州大学附属儿童医院2019年1月至2021年1月收诊的40例CAH新生儿作为试验组,同期选取50例健康体检新生儿作...
The aim of the present study was to elucidate the time course according to which changes in circulating concentrations of progesterone influence pulsatile secretion of LH and secretion of 17β-estradiol. Our working hypothesis was that changing the dose of progesterone would result in changes in freq...
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(Speiseret al., 1985). This mutation results in an enzyme with 50% of normal activity when 17-hydroxyprogesterone is the substrate but only 20% of normal activity for progesterone (Tusie-Lunaet al., 1990; Wu and Chung, 1991). The mutant enzyme is not normally localized in the ...
In the 4 patients with a ratio) 1, 1 had a 17 hydroxy- progesterone response to ACTH similar to the patients with par- tial 21 hydroxylase deficiency. However she did not respond to glucocorticoid therapy. Of the 10 PCOS patients with a 17 OH-Preg ratio< l, 2 had a 17 hydroxy ...
ctkehtienergre(AaBcbGtiiMonnc,uwLbaaabs- tion, from the values obtained. The appraisals were performed in triplicate. by RPoladsrmígauleezveelts aolf.6T7 ,a1n1d-KpTre,vE i2oaunsldy progesterone (P) used in gilthead were quantified by ELISA following the method described s ea...
phe and 17ohp levels were determinated by umtest pku and umelisa 17oh progesterone neonatal, respectively. 19.5% of 3043 newborns samples exhibited unsatisfactory spots. concordance correlations studies between mv y mnv showed the precision and accuracy were affected by quality of the samples. false...
SERUM 17-OH PROGESTERONE LEVELS IN PRERATURES BY DIRECT 22 AND POST EXTRACTION ASSAYS PURING THE F I R S T SEVEN DAYS OF L I F E . Warman r4, n o A, R i v a r o l a MA, N B iz el z g o o r P, os k C y ha A. l e r S E, er v M ic ac io ei d r ...
In the ovarian follicle, the Theca Cells (TCs) have two main functions: preserving morphological integrity and, importantly, secreting steroid androgen hormones. TCs express the essential enzyme 17α-hydroxylase/17,20-desmolase (CYP17), which permits the conversion of pregnenolone and progesterone int...