Definition A primarily growth stimulatory signaling molecule resulting from the metabolism of LA by 15-lipoxygenase-1 in cancer cells. Melatonindoi:10.1007/978-3-540-47648-1_2897M R BuchananM C BertomeuS J BristerT A HaasSpringer Berlin HeidelbergWiener Klinische Wochenschrift...
货号:SCFC-31318; 中文名:13(S)-羟基-9(Z),11(E)-十八碳二烯酸; 英文名:13(S)-hydroxy-9(Z),11(E)-octadecadienoic acid; CAS:[29623-28-7];
Abstract The most abundant polyunsaturated fatty acids (PUFAs) in human skin are linoleic acid (LA, 18: 2n-6) and arachidonic acid (AA, 20: 4n-6) (1, 2). LA is metabolized by epidermal 15-lipoxygenase into predominantly 13-hydroxyoctadecadienoic acid (13-HODE). An analysis of lipoxygenas...
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2014. Differential cell growth/apoptosis behaviour of 13-hydroxyoctadecadi- enoic acid enantiomers in a colorectal cancer cell line. Am. J. Physiol. Gastrointest. Liver Physiol. 307, G664-G671. http://dx.doi.org/10.1152/ajpgi.00064.2014...
A new method of preparation of optically active 13-S-hydroxyoctadecadienoic acid (13-HODE) is described. The key chemical step involves the coupling of methyl Z-10-iododec-9-enoate and tri-n-butyl(3(S)-dimethyl-tert-butylsilyloxy)-oct-l-enylstannane using a palladium (II) catalyst. The...
pharmacological levels of the pineal hormone melatonin exhibit substantial anticancer activity in tissue-isolated rat hepatoma 7288CTC via melatonin receptor-mediated blockade of tumor uptake of linoleic acid (LA) and its metabolism to the mitogenic signaling molecule 13-hydroxyoctadecadienoic acid (13-...
In this study, we investigated the regulation of PKC-alpha in murine B16 amelanotic melanoma (B16a) cells by the monohydroxy fatty acids 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE] and 13(S)-hydroxyoctadecadienoic acid [13(S)-HODE]. 12(S)-HETE induced a translocation of PKC-alpha ...
9-Hydroxyoctadecadienoic acid (9-HODE); 9-oxo-octadecadienoic acid (9-oxoODE); 13-hydroxyoctadecadienoic acid (13-HODE); 13-oxo-octadecadienoic acid (13-oxoODE); transient receptor potential vanilloid 1 (TRPV1; VR1). Science-Business eXchange 2, 1577 (2009). https://doi.org/10.1038/sci...
英文别名: (±)-13-HODE [9,10,12,13-3H] ((±)-13-Hydroxy-9Z,11E-octadecadienoic acid) C18H32O3 中文名: 中文别名: CBNumber: CB712203155 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 (±)-13-HODE [9,10,12,13-3H] ((±)-13-Hydroxy-9Z,11E-...