虽然 CNN 对 “边界” 病例的预测准确性较低,但基于区域 5 级评分得出的二进制全局评分在扫描层面的二进制分类准确率高达 95% 以上。该研究表明,基于 CNN 的 [123I] FP-CIT 摄取 5 级分类在临床上具有实用准确性,可用于自动识别不确定的边界病例和 “非典型” 模式,减少 DAT-SPECT 结构化报告的阅读时间并...
single-photon emission computed tomography (SPECT)Presynaptic dopaminergic deficiency on dopamine transporter imaging supports a clinical diagnosis of Parkinson's disease and correlates with the severity of rigidity and bradykinesia. Baseline dopaminergic deficiency predicts clinical severity, but the relationship...
患者接受了连续的123I-FP-CIT SPECT成像,首先在常规相机上采集30分钟,然后立即使用360°-CZT相机分别以纹状体和大脑为焦点进行两次15分钟的采集,CZT相机的总采集时间为30分钟。 SPECT Imaging Patients underwent consecutively123I-FP-CI...
123I‐FP‐CIT SPECTcaudate nucleusneuropsychological testsBackground: The p.A53T point mutation in the α‐synuclein gene (SNCA) is a rare but highly relevant cause of autosomal dominant Parkinson's disease (PD). Objectives: The objective of this study was to assess striatal dopaminergic ...
1871 Objectives 123I-FP-CIT-SPECT provides an imaging biomarker of nigrostriatal neuronal integrity, allowing the differential diagnosis of Parkinsonian syndrome (PS). There have been reports on normal FP-CIT uptake in presynaptic PS, referred to as scans without evidence of dopaminergic deficit (SW...
Diagnostic accuracy of 123I-FP-CIT SPECT in possible dementia with Lewy bodies. Br J Psychiatry 2009;194:34-9.O'Brien JT, McKeith IG, Walker Z, et al. Diagnostic accuracy of 123I-FP-CIT SPECT in possible dementia with Lewy bodies. Br J Psychiatry. 2009;194: 34-39....
may help to distinguish a drug-induced parkinsonism from an idiopathic Parkinson's disease. We herein describe two cases of patients with schizophrenia or schizoaffective disorder, in whom the Parkinson's disease was proved by the 123I-FP-CIT SPECT and an adequate neurological treatment was estab...
123I-FP-CIT SPECT (DaTScan) is a complementary tool in the differential diagnoses of patients with incomplete or uncertain Parkinsonism. Additional application of DaTScan enables the categorization of Parkinsonian disease with dementia (PDD), and its differentiation from pure AD, and may further ...
1834 Objectives I-123-FP-CIT-SPECT is increasingly used to differentiate between Alzheimer's dementia (AD) and dementia with Lewy bodies (DLB). The role of I-123-FP-CIT-SPECT in frontotemporal dementia (FTD) is rather unclear, albeit nigrostriatal involvement may occur. The aim of this study...
Tossici-Bolt L, Hoffmann SMA, Kemp PM, Mehta RL, Fleming JS. Quantifi- cation of [123I]FP-CIT SPECT brain images: an accurate technique for mea- surement of the specific binding ratio. Eur J Nucl Med Mol Imaging. 2006;33: 1491-1499....