Abstract: 149 ACCELERATED ATHEROSCLEROSIS WITH 11B-HSD2-DEFICIENCY IS ASSOCIATED WITH INCREASED INFLAMMATION IN EARLY STAGES OF PLAQUE DEVELOPMENTMineralocorticoid receptor (MR) activation is proinflammatory and proatherogenic. Antagonism of MR improves survival in humans with congestive heart failure caused ...
复方甘草酸苷片对局灶节段性肾小球硬化大鼠肾功能及CYP11B2、11b-HSD2基因表达的影响 唐玥雯1,2, , 杨汝春1,3, , , 万凤1,3, 张华琴1,3, 汤绚丽1,3, 王永钧1,3 1. 浙江省肾脏疾病防治技术研究重点实验室, 杭州 310000; 2. 杭州市丁桥医院肾内科, 杭州 310021; ...
Crystal structure of 11b-HSD1 double mutant (L262R, F278E) in complex with (1S,4S)-4-[8-(2-fluorophenoxy)[1,2,4]triazolo[4,3-a]pyridin-3-yl]bicyclo[2.2.1]h... S Sheriff 被引量: 0发表: 2014年 An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell ...
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11b-HSD2 inhibition by the pesticide thiram: The role of cysteine residuesMeyer, A.Odermatt, A.TOXICOLOGY LETTERS
STIMULATION OF 11B-HSD2 EXPRESSION TO IMPROVE HORMONAL THERAPY OF STEROID-DEPENDENT DISEASEA method of treating a steroid-dependent disease in a subject is described. The method includes providing steroid hormonal therapy to the subject while inhibiting glucocorticoid receptor activity, or by stimulating...
738: Placental 11b-HSD2 and cardiometabolic heath indices in infancydoi:10.1016/j.ajog.2018.11.761Zhong-Cheng Luo LuoElsevier BVAmerican Journal of Obstetrics and Gynecology
Tzschoppe A, Fahlbusch F, Seidel J, Dorr HG, Rascher W, Goecke TW, Beckmann MW, Schild RL, Struwe E, Dotsch J: Dexamethasone stimulates the expression of leptin and 11beta-HSD2 in primary human placental trophoblastic cells. Eur J Obstet Gynecol Reprod Biol 2011, 156(1):50-55. Epub...
figure s4 p1acenta1 11b hsd2 and umbi1ica1 cord b1ood cortiso1 versus newbom gender notes p for mann whitney s test the numerica1 va1ues next to the boxes represent medianFigure S. Correlation between placental β-HSDumbilical cord blood cortisol in three\u001Fmodes of delivery. Notes:...
To systematically review studies evaluating the association of HSD11B1 gene expression in abdominal adipose tissue and HSD11B1 polymorphisms with obesity, the metabolic syndrome (MetS), and type 2 diabetes (T2DM), we conducted a search in MEDLINE, SCOPUS, and Cochrane Library databases in April ...