Comparative antiproliferative effects of 111In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR- positive breast cancer cells. Nucl Med Biol. 2002;29:693-699.Chen P,Mrkobrada M,Vallis KA,et al.Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and ...
Relationship Between Induction of Phosphorylated H2AX and Survival in Breast Cancer Cells Exposed to 111In-DTPA-hEGF doi:10.2967/jnumed.108.051805Journal of Nuclear MedicineZhongli CaiZhuo ChenBailey, Kristy E.Scollard, Deborah A.Reilly, Raymond M.Vallis, Katherine A....
Reilly, Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software. Int J Radiat Biol, 2009. 85(3): p. 262-71.Z. Cai, K.A. Vallis, R.M. Reilly, Computational analysis of the...
111In-DTPA-hEGFbreast cancer cellsDNA double strand breaksImage-FImage-JPurpose: To develop a simple method for the quantification of γ-H2AX focus number, density and size. Methods: MDA-MB-468 human breast cancer cells were treated overnight with 111In-diethylenetriaminepentaacetic acid human ...
Tolmachev V, Orlova A, Wei Q, Bruskin A, Carlsson J, Gedda L (2004) Comparative biodistribution of potential anti-glioblastoma conjugates [111In]DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice. Cancer Biother Radiopharm 19:491-501
hEGF (MG111) given i. v. significantly and dose-dependently suppressed the reduction in gastric mucosal potential-difference (PD) induced by 30 % ethanol in rats. Pretreatment with indomethacin did not affect its effect, thereby suggesting that endogenous prostaglandins will not be involved in the...
Introduction EGFt is a truncated form of human epidermal growth factor (hEGF) that is non-biologically active but retains binding and internalization into EGFR-positive cells. Our aim was to compare EGFt and hEGF for delivery of 111In to human breast cancer (BC) cells and tumors and evaluate...