THC 被 快速代谢为 11-羟基-∆9 -四氢大麻酚 (11-0H-THC),然后转化为 11-nor-∆9 -THC-9- 羧酸 (THC-COOH)。 检测尿液中的 THC 代谢物(主要为 THC-COOH)可反映出之前对 THC 的接 触,但无法反映损害程度。检测血液中的 THC 及其代谢物可以更好地反映 近期毒品使用情况,并且在损害测试时体现出...
安捷伦液质6470用于测定全血,符合行业标准暂无。适用THC、THC-COOH 和 11-OH-THC项目。 Agilent 6470 三重四极杆液质联用系统 Agilent 6470 三重四极杆液质联用系统提供了更高的灵敏度、精度和扫描速度,使您能够简化分析流程。即便稀释样品或减少样品量也能让您完全信赖结果的准确性。久经考验的稳定性和可靠性意味...
9-tetradydrocannabinol-9-carboxylic acid (THCCOOH) in plasma was developed in order to be assayed by high-performance liquid chromatography and tandem mass spectrometry (HPLC-MS/MS). Methods: The samples were extracted by liquid/liquid extraction over solid support of an ...
THCand other forms of cannabinoids are lipid soluble and can enter into body tissues rapidly. THC is rapidly metabolized to 11-hydroxy-∆9-tetrahydocannabinol (11-OH-THC), which is thenconverted into 11-nor-∆9-THC-...
The purpose of this research is to evaluate the distribution of 螖9-tetrahydrocannabinol (THC), and its metabolites, 11-hydroxy-tetrahydrocannabinol (11-OH-THC) and THC-COOH, in postmortem fluid and tissue specimens from 11 fatal aviation accident cases (2014-2015) previously found positive for ...
Quantification of 9-tetrahydrocannabinol (THC), 11-OH-THC, THC-COOH, hexahydrocannabinol and cannabidiol in human plasma and blood by liquid chromatography–tandem mass spectrometryThe presented method is sensitive, specific, easy to handle and does not require high-end equipment. Since its ...
For this reason, the determination of 11‐nor‐9‐carboxy‐Δ-9-tetrahydrocannabinol (THC‐COOH) has been proposed by the Society of Hair Testing (SoHT) in order to prove active cannabis consumption. The identification of THC-COOH in hair will continue to be complicated by its acidic nature ...
THC intra- and inter-subject whole blood/plasma ratio variances were large (0.14 and 0.09 for THC, 0.14 and 0.28 for THCCOOH). Escalating daily oral THC yielded 11-OH-THC and THCCOOH, but not THC, accumulation in plasma. THC concentrations remained >1ng/mL, 19.5h after admission and ...
Nadulski T,Sporkert F,Schnelle M,et a1.Simultaneous and sensitive analysis of THC,1 1-OH-THC,THC-COOH,CBD, and CBN by GC-MS in plasma after oral application of small doses of THC and cannabis extract[J],J Anal Toxicol,2005, 29:782-789...
Whole blood, plasma and urine Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC (11-OH-THC) and Delta9-carboxy-THC (THCCOOH) concentrations document cannabis exposure. Clinical data generally are derived from specimens obtained after single THC administrations. Few data are available from daily ...