1-Aminobenzotriazole (ABT) 是一种不可逆的细胞色素 P450 非特异性抑制剂。 规格价格库存数量 25 mg¥ 292现货 50 mg¥ 410现货 100 mg¥ 497现货 200 mg¥ 671现货 500 mg¥ 1,347现货 1 mL x 10 mM (in DMSO)¥ 460现货 大包装 & 定制 ...
1-氨基苯并三唑1-Aminobenzotriazole又称ABT 1-Aminobenzotriazole是细胞色素P450(P450)的非特异且不可逆抑制剂。 MCE的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务 生物活性 体外研究 1-Aminobenzotriazole(ABT)单独显著增加两种不同肝细胞中CYP2B6的表达水平(分别为7.3倍和10.8倍)。与1-Ami...
体内:口服 1-Aminobenzotriazole (ABT) (100 mg/kg,给药前 2 小时) 可降低大鼠静脉注射普鲁卡因胺的清除率 (45%),同时尿液中 N-乙酰基普鲁卡因胺与普鲁卡因胺的比率降低 (0.74 对 0.21) 和血浆 (曲线下面积比 0.59 与 0.11)。使用 1-Aminobenzotriazole[2],普鲁卡因胺的尿液回收率从 18% 增加到 30%,而尿...
1-Aminobenzotriazole (ABT) is a suicide substrate of both hepatic and pulmonary cytochromes P450. The present studies were designed to compare the effects of ABT on hepatic and renal metabolism. Hepatic and renal microsomes and cytosol were prepared from male Sprague-Dawley rats following ABT ...
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Both safeners and ABT derivatives significantly elevated the GST activity in the concentrations needed for effective safening action. ABT is considered as an inhibitor of plant cytochrome P450 monooxygenases (P450) and, because of this, used to study herbicide mode of action. Our data indicate that...
1-aminobenzotriazole (ABT), the cytochrome P450 suicide inhibitor, sensitizes rats to zymosan induced-multiple organ failure 1841998 Abstracts The American Pediatric Society and The Society for Pediatric Researchdoi:10.1203/00006450-199804001-00205Joseph Carcillo...
The objectives of this study were to determine the effect of 1-aminobenzotriazole (ABT-1) on the growth and physiology of Tamarix chinensis under salt stress and to determine a suitable ABT-1 concentration and soil salinity (Sc) for propagating T. chinensis-cuttings. Cuttings were soaked in ...
1-Aminobenzotriazole (ABT) is a non-isoform specific, time-dependent inhibitor of cytochrome P450 (CYP) enzymes used extensively in preclinical studies to determine the relative contribution of oxidative metabolism. Although ABT has been widely used, the extent and duration of its inhibitory effect ...