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The main problem with eye drops is that most substances do not cross the ocular barriers to reach a suitable therapeutic concentration in the retina. We have recently provided evidence that PACAP1-27, the shorter form of PACAP, crosses the ocular barriers and reaches the retina in an amount ...
Curiously, the aromatic resonances for the η6-cym protons do not feature as two doublets as in the spectrum of the respective dimer precursors. The 1D NMR data were corroborated by those of the COSY, HSQC, and other related correlated techniques, and these data are presented only for Ru3 ...
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