Differential expression and function of two homologous subunits of yeast 1,3-beta-d-glucan synthase Mol Cell Biol, 15 (1995), pp. 5671-5681 10.1128/MCB.15.10.5671 View in ScopusGoogle Scholar 15. T Mio, M Adachi
Glucan endo-β(1 → 3)-d-glucosidases, officially classified as endo-β(1 → 3)-glucanases (EC 3.2.1.39) and exo-β(1 → 3)-glucanases (EC 3.2.1.58), are widely distributed among higher plants, fungi, and bacteria. These enzymes catalyze hydrolysis of β(1 → 3)-glucosidic linkag...
(1,3)-beta-D-glucan synthase 体外研究 Enfumafungin (24-48 h) has MICs of less than 0.5 μg/mL against theCandidaandAspergillusspecies tested and it is inactive againstCryptococcus, including the decapsulated form (MY2062). 体内研究
靶点 (1,3)-beta-D-glucan synthase[1] 体外研究 Enfumafungin(24-48小时)的MIC小于0.5μg/mL抗念珠菌和曲霉菌,对隐球菌无效,包括脱囊形式(MY2062)[1]。 体内研究 恩复马芬净(50-200mg/kg;i、 每天两次,连续两天)使c.f.u.在c。白色念珠菌,ED90为90 mg/kg[1]。
The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1, 3-beta-D-glucan synthase. Proc Natl Acad Sci. 1994;91(26):12907–11. https://doi.org/10.1073/pnas.91.26.12907. Article CAS PubMed PubMed Central Google Scholar ...
结论血清β-(1,3)-D-葡聚糖在新生儿侵袭性真菌感染中呈高表达水平,可为临床诊断提供重要的参考依据,值得推行。 关键词: 血清β-(1,3)-D-葡聚糖;新生儿;侵袭性真菌感染;诊断价值 ABSTRACT ObjectiveTo investigate the expression level of serum β-(1,3)-D-glucan in invasive fungal infection of neonates...
New derivatives of caffeic acid and quinic acid were synthesized and their anti-fungal and inhibitory activities on fungal 1,3-β-glucan synthase were determined in comparison with those of the corresponding chlorogenic acid derivatives. All the chlorogenic, quinic and caffeic acid derivatives that wer...
摘要:真菌β-1,3-葡聚糖合酶(β-1,3-glucansynthase,GS)是由催化亚基和调节亚基组成的酶复合体。在酿酒 酵母中GS的催化亚基是由2个序列高度相似的基因FKS1和FKS2编码的,在其他酵母中也存在多个与酿酒酵 母FKS相似的基因,而在大多数丝状真菌中只存在1个FKS基因。文中主要介绍酿酒酵母和其他重要真菌中 ...
Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2]. Enfumafungin (24-48 h) has ...
1-3-glucansynthase抑制剂是科学研究中的重要工具,用于调节相关生物过程。店内提供的基准试剂中含有高效成分,专为支持体外细胞生长和分化设计,有效成分含量高达99%。该试剂规格为10ml,储存方便,只需置于-20℃下保存。此外,试剂由层粘连蛋白、IV型胶原蛋白等多种成分组成,品质过硬,确保实验结果的准确性。现在店内恰好...