(1,3)-beta-D-glucan synthase 体外研究 Enfumafungin (24-48 h) has MICs of less than 0.5 μg/mL against theCandidaandAspergillusspecies tested and it is inactive againstCryptococcus, including the decapsulated form (MY2062). 体内研究
The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase In Saccharomyces cerevisiae, mutations in FKS1 confer hypersensitivity to the immunosuppressants FK506 and cyclosporin A, while mutations in ETG1 confer re... CM ...
albicans were grown after dilution of a stationary phase inoculum of yeast cells into fresh medium at 30 degrees C and 40 degrees C respectively and the specific activities of (1,3)-beta-D-glucan synthase, obtained from budding and filamentous cultures harvested during the first 3 h of their...
结论血清β-(1,3)-D-葡聚糖在新生儿侵袭性真菌感染中呈高表达水平,可为临床诊断提供重要的参考依据,值得推行。 关键词: 血清β-(1,3)-D-葡聚糖;新生儿;侵袭性真菌感染;诊断价值 ABSTRACT ObjectiveTo investigate the expression level of serum β-(1,3)-D-glucan in invasive fungal infection of neonates...
The β—glucan synthase had different properties from other preparations which bring about the synthesis of β—1,3—glucans (callose) and mixed β—1,3... G Piro,A Zuppa,GDH Northcote - 《Planta》 被引量: 102发表: 1993年 Synergistic activation of 1,3-beta-D-glucan synthase by Ca2+ an...
Article: Correlation of cilofungin in vivo efficacy with its activity against Aspergillus fumigatus (1,3)-beta-D-glucan synthase
The enzyme that produces paramylon is a glycosyltransferase commonly known as paramylon synthase (EC 2.4.1.34; UDP-glucose: 1,3-β-D-glucan 3-β-D-glucosyl transferase). This enzyme uses UDP-glucose as its main substrate. In 2001, Bäumer et al. isolated and partially purified para...
mutations in FKS1 confer hypersensitivity to the immunosuppressants FK506 and cyclosporin A, while mutations in ETG1 confer resistance to the cell-wall-active echinocandins (inhibitors of 1,3-beta-D-glucan synthase) and, in some cases, concomitant hypersensitivity to the chitin synthase inhibitor ni...
英文别名: 1,3-beta-glucan synthase 中文名: 中文别名: CBNumber: CB01390342 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 0 1,3-beta-glucan synthase化学性质 安全信息1,3-beta-glucan synthase性质、用途与生产工艺 1,3-beta-glucan synthase 上下游产品信息 上游原料 下游...
So it is possible to discover glucan synthase inhibitor with broad-spectrum capacity. 当FKS1缺失时,酵母细胞对葡聚糖合酶抑制剂高度敏感。补充资料:合成酶 分子式:CAS号:性质:能催化由两种组分合成一个分子的有关酶的总称。在合成过程中,需要由ATP或其他三磷酸核苷酸的高能磷酸键提供能量。 说明:补充资料仅...