(1,3)-beta-D-glucan synthase 体外研究 Enfumafungin (24-48 h) has MICs of less than 0.5 μg/mL against theCandidaandAspergillusspecies tested and it is inactive againstCryptococcus, including the decapsulated form (MY2062). 体内研究
Enzyme Activity:endo-1,3(4)-β-Glucanase EC Number:3.2.1.6 CAZy Family:GH16 CAS Number:62213-14-3 Synonyms:glucanendo-1,3(4)-beta-D-glucosidase Source:Trichodermasp. Molecular Weight:32,000 Concentration:Supplied at ~ 50 U/mL Expression:Purified fromTrichodermasp. ...
结论血清β-(1,3)-D-葡聚糖在新生儿侵袭性真菌感染中呈高表达水平,可为临床诊断提供重要的参考依据,值得推行。 关键词: 血清β-(1,3)-D-葡聚糖;新生儿;侵袭性真菌感染;诊断价值 ABSTRACT ObjectiveTo investigate the expression level of serum β-(1,3)-D-glucan in invasive fungal infection of neonates...
Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2]. Enfumafungin (24-48 h) has ...
Glucan endo-β(1 → 3)-d-glucosidases, officially classified as endo-β(1 → 3)-glucanases (EC 3.2.1.39) and exo-β(1 → 3)-glucanases (EC 3.2.1.58), are widely distributed among higher plants, fungi, and bacteria. These enzymes catalyze hydrolysis of β(1 → 3)-glucosidic linkag...
The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1, 3-beta-D-glucan synthase. Proc Natl Acad Sci. 1994;91(26):12907–11. https://doi.org/10.1073/pnas.91.26.12907. Article CAS PubMed PubMed Central Google Scholar ...
1-3-glucansynthase抑制剂在支持体外细胞生长和分化方面扮演重要角色,是生化研究不可或缺的试剂。店内提供的抑制剂,如Matrigel 标准型基质胶,含有99%的有效成分,PH范围1-13,适用于各种实验需求。且产品储存稳定,置于-20℃下即可。若您需要高品质、质量有保证的1-3-glucansynthase抑制剂,或想了解更多详情,请随时联...
BGS4(beta-glucansynthase)。目前只有 BGS4基因 产物(Bgs4p)是唯一确定为 β-1,3-葡聚糖合酶复合 体成分的蛋白质,在维持细胞分裂、极性生长和 孢子萌发方面是必需的。BGS4基因缺失突变菌株 (bgs4)的细胞壁 β-葡聚糖减少,葡聚糖合酶催化 活性下降,细胞形态有缺陷 [6] 。 丝状真菌中的构巢曲霉(Aspergillu...
靶点 (1,3)-beta-D-glucan synthase[1] 体外研究 Enfumafungin(24-48小时)的MIC小于0.5μg/mL抗念珠菌和曲霉菌,对隐球菌无效,包括脱囊形式(MY2062)[1]。 体内研究 恩复马芬净(50-200mg/kg;i、 每天两次,连续两天)使c.f.u.在c。白色念珠菌,ED90为90 mg/kg[1]。
It is an antifungal compound that acts on the fungal cell wall as a (1,3)-beta-D-glucan synthase inhibitor. in vitro Enfumafungin (24-48 h) has MICs of less than 0.5 μg/mL against the Candida and Aspergillus species tested and it is inactive against Cryptococcus , including the de...