fungalantifungalcalcineurincalciumpathwaysignaling ComponentsoftheCalcium-CalcineurinSignalingPathwayinFungal CellsandTheirPotentialasAntifungalTargets ShuyuanLiu, a YinglongHou, b WeiguoLiu, d ChunyanLu, d WeixinWang, c ShujuanSun d SchoolofPharmaceuticalSciences,ShandongUniversity,Jinan,ShandongProvince,People’s...
近日,由美国加州大学伯克利分校栾升教授领导的研究团队在PNAS发表了题为"TORC pathway intersects with a calcium sensor kinase network to regulate potassium sensing in Arabidopsis"的研究论文。该研究首次揭示了钾营养激活植物的TORC,以及植物通过TORC和CBL2/3-CIPKs信号通路之间的相互调控来平衡植物生长和低...
Objectlve To explore the signal pathway of calcium-sensing receptor (CaSR) in hypoxia-induced airway mucous hypersecretion. Methods Cultured human airway epithelial cells 16HBE by hypoxia incubator (37 oC,94%N2-1%O2-5%CO2) and divided into 6 groups:control group,hypoxia group,CaSR specific acti...
摘要 目的 探讨大豆异黄酮(SI)减轻脑缺血再灌注(I/R)引起钙超载的作用机制。方法 将48只SD大鼠采用随机数法分为4组:假手术组(Sham组)、脑缺血再灌注模型组(I/R组)、病毒空载组(NC组)、Frizzled-2敲...展开更多 Objective To explore the mechanism by which soybean isoflavone(SI)reduces calcium overload...
旁腺细胞中克隆出钙敏感受体(calciumsensingre ceptor,CaSR),随后在人甲状旁腺 [3] 和大鼠的肾 脏 [4] 中也发现了CaSR的表达,进一步研究发现机 体内钙离子(Ca 2+ )可以作为CaSR的天然内源性 配体,具有细胞外第一信使的作用 [5-7] 。当Ca
Fig 2 Effects of PGF2α at different concentrations on the intra2 cellular free calcium concentration ( [ Ca2 + ] i ) of cardiac myocytes and the inhibition of CsA ( 10 - 6 mol/L ) on the elevated [ Ca2 + ] i induced by PGF2α 10 - 7 mo l/L. 33 P < 0. 01 vs control; ...
图2 NE、肝素、钙对肥胖小鼠脂肪组织质量的影响Fig.2 Effect of NE,heparin,calcium on adipose tissue mass of obese mice 2.4 肥胖小鼠血脂指标的变化 由表4可知,与对照组相比,肝素组、钙组、钙+NE组和钙+肝素组小鼠的TG和TC浓度均极显著下降(P<0.01),而HDL-C浓度均极显著升高(P<0.01),NE组小鼠的TC浓...
热应激刺激时,动物体产生一系列生理变化 来提高机体的耐受性,而本文旨在阐述钙(calcium,Ca2+)一钙调蛋白(calcium-activated shock 与的耐热信号的转导机制,即热应激蛋白(heat 浓度上升,激活CaM及其表达量的增加,随即CaM作用于其下游的2种靶蛋白,即2条信号转导支路来提 shock 高热激转录因子1(heat calmodulin—...
Conclusion: CASR, VDR, and PTH1R are involved in the occurrence of calcium-containing kidney stones, and may participate in the mechanism of calcium containing kidney stones through the CASR/VDR/PTH1R signaling pathway.李静玲柯坤彬王振丞
wntβ-catenin信号通路在主动脉瓣钙化机制中的调控作用-regulation of wnt β - catenin signaling pathway in aortic valve calcification.docx,英文缩略词表英文缩写英文名称中文名称APC GSK-3β DSHα-SMAox-LDL IHCRT-PCRMg Ml MinFBSAdenomatous poliosis coli Glycoge