Latina singer Rebekah Del Rio plays herself at a nightclub, "lip-synching" an a cappella version of "Llorando," Roy Orbison's song "Crying" in Spanish translation (much as Dean Stockwell lip-synchs Orbison's "In Dreams" in Lynch's earlier film Blue Velvet, except that Del Rio...
好莱坞的穆赫兰道上，一个名叫丽塔（劳拉·哈灵 饰）的女人遇上了一场车祸。车祸中的另外两个看上去显然不怎么正经的男人当场丧命，但丽塔幸运地死里逃生。但是她完全失忆了，甚至连自己的名字也无法记起。她从车里爬出来，跌跌撞撞地来到一座公寓，藏身于公寓外的灌木丛中。与此同时，立志要做演员的金发女孩...