PI3K/Akt抑制剂组尾静脉注射PI3K/Akt抑制剂LY294002,空白对照组,荷瘤组尾静脉注射等体积生理盐水.治疗结束后取前列腺组织,采用Western blotting检测磷酸化雄激素受体AR(p-AR),磷酸化蛋白激酶(p-Akt),雄激素受体剪接变异体7(AR-V7);免疫荧光双重染色(FITCCY3)法检测降钙素(Calcitonin)和钙黏蛋白E(E-cadherin)...
PI3K/Akt抑制剂组尾静脉注射PI3K/Akt抑制剂LY294002,空白对照组、荷瘤组尾静脉注射等体积生理盐水.治疗结束后取前列腺组织,采用Western blotting检测磷酸化雄激素受体AR(p-AR)、磷酸化蛋白激酶(p-Akt)、雄激素受体剪接变异体7(AR-V7);免疫荧光双重染色(FITC-CY3)法检测降钙素(Calcitonin)和钙黏...
4) PI3K/Akt 磷脂酰肌醇3激酶/蛋白激酶B 1. Results The PI3K/Akt pathway was activated by rHuEPO after status epilepticus was kindled by pentylenetetrazol in rats, with activated expressions of caspase-9 and XIAP. 结果在PTZ点燃大鼠SE后rHuPO活化了磷脂酰肌醇3激酶/蛋白激酶B途径,激活了半胱氨酸...
Results The PI3K/Akt pathway was activated by rHuEPO after status epilepticus was kindled by pentylenetetrazol in rats, with activated expressions of caspase-9 and XIAP. 结果在PTZ点燃大鼠SE后rHuPO活化了磷脂酰肌醇3激酶/蛋白激酶B途径,激活了半胱氨酸天冬氨酸蛋白酶9、X-连锁凋亡抑制蛋白的表达;rHuEPO...