氨基酸的侧链保护基团 氨基酸 侧链官能团 保护基 保护基结构式 保护基脱除条件 Arg Pbf 95%TFA ,30min Asp/ Glu OtBu 90%TFA ,30min OAll Pb(Ph3P)4-AcOH-NMM ;Pb(Ph3P)4-PhSiH3inDCM ,10-30min Asn/ Gln Trt 90%TFA ,30-60min Cys Trt 90%TFA ,30-60min Acm Hg(Ⅱ);Ag(Ⅰ); Tl(Ⅲ); ...
内容提示: 氨基酸的侧链保护基团 保护基 氨基酸 侧链官能团 保护基结构式 保护基脱除条件 Arg NHNH2NH Pbf OSOHNO 95%TFA 30min Asp/ Glu OHO OtBu OO 90%TFA 30min OAll OO Pb(Ph3P)4-AcOH-NMM Pb(Ph3P)4-PhSiH3 in DCM 10-30min Asn/ Gln NH2O Trt NH 90%TFA 30-60min Cys SH Trt S 90...
氨基酸的侧链保护基团 氨基酸侧链官能团保护基保护基结构式保护基脱除条件NHO Arg95%TFA,30minPbfOHNNH2NHS O O 90%TFA,30minOtBuOOAsp/ P)-AcOH-NMM;Pb(PhGlu34OOH Pb(PhP)-PhSiHinDCM,OAll343 O10-30minOAsn/ 90%TFA,30-60minTrtNHGlnNH2
氨基酸的侧链保护基团氨基酸侧链官能团保护基保护基结构式保护基脱除条件NHOArg95%TFA,30minPbfOHNNH2NHSOO90%TFA,30minOtBuOOAsp/P)-AcOH-NMM;Pb(PhGlu34OOHPb(PhP)-PhSiHinDCM,OAll343O10-30minOAsn/90%TFA,30-60minTrtNHGlnNH290%TFA,30-60minTrtSOHg(?);Ag(?);Tl(?);CysSHAcmSNSiClPh(SO)Ph-...
氨基酸的侧链保护基团.doc氨基酸的侧链保护基团 氨基酸 侧链官能团 保护基 保护基结构式 保护基脱除条件 Arg Pbf 95%TFA,30min Asp/ Glu OtBu 90%TFA,30min OAll Pb(Ph3P)4-AcOH-NMM;Pb(Ph3P)4-PhSiH3inDCM,10-30min Asn/ Gln Trt 90%TFA,30-60min Cys Trt 90%TFA,30-60min Acm Hg(Ⅱ);Ag(Ⅰ...
1、.氨基酸的侧链保护基团氨基酸侧链官能团保护基保护基结构式保护基脱除条件argpbf 95%tfa ,30minasp/gluotbu90%tfa ,30minoallpb(ph3p)4-acoh-nmm ;pb(ph3p)4-phsih3 in dcm ,10-30minasn/glntrt90%tfa ,30-60mincystrt90%tfa ,30-60minacmhg();ag(); tl();ph(so)ph-ch3sicl3tbuhf(20);hg(...
甘氨酸、丙氨酸、丝氨酸等。根据百度查询：氨基酸没有侧链保护基团的包括但不限于以下几个：甘氨酸、丙氨酸、丝氨酸、脯氨酸、天冬氨酸、谷氨酸、异亮氨酸、亮氨酸、苏氨酸等。
氨基酸ArgAsp/GluAsn/GlnCys侧链官能团NHNH 2HOOHONH 2SH氨基酸的侧链保护基团保护基 保护基结构式OPbfH ONSOOOtBuOOOAllOTrt NHTrt SOAcmS NHtBuSSStBu S保护基脱除条件95%TFA ,30min90%TFA ,30minPb(Ph3P)4-AcOH-NMM ; Pb(Ph3P)4-PhSiH 3 in DCM , 10-30min90%TFA ,30-60min90...
1、氨基酸的侧链保护基团氨基酸侧链官能团保护基保护基结构式保护基脱除条件NHoArg95%TFA,30minPbf0HNNH2NHSOO90%TFA,30minOtBuOOAsp/P)-AcOH-WM;Pb(PhGlu3400HPb(PhP)-PhSiHinDCM,OAll343010-30minOAsn/90%TFA,30-60minTrtNHGlnNH290%TFA,30-60minTrtSOHg(?);Ag(?);Tl(?);CysSHAcmSNSiClPh(S0)Ph...
氨基酸的侧链保护基团氨基酸侧链官能团保护基保护基结构式保护基脱除条件NHOArg95%TFA30minPbf0HNNH2NHS0090%TFA30minOtBuOOAsp/P-AcOH-NMM;PbPhGlu3400HPbPhP-PhSiHinDCM0A11343010-30minOAsn/90%TFA30-60minTrtNHGl...