核因子kappa B受体活化因子RANK配体龈沟液目的:探讨正畸保持期牙周龈沟液中骨保护素(osteoprotegerin,OPG)和核因子kappa B受体活化因子配体水平(receptor activator of nuclear factor kappa B ligand,RANKL)的变化及相应牙周组织OPG和RANKL表达的变化,为预测保持期牙周骨组织状态是否稳定提供依据.方法:选择6周龄雄性...
胞核因子κB受体活化因子/细胞核因子κB受体活化因子配体/骨保护因子(RANK/RANKL/OPG)系统在破骨细胞的活化、发育、成熟过程中起关键性作用,近年研究发现该系统也广泛参与骨肿瘤发生、肿瘤骨转移、细胞凋亡,这些研究为相关疾病的治疗提供了新的思路和方法,如重组OPG和人类RANKL单克隆抗体AMG-162的应用。补充...
核因子-κB受体活化子配体1. Objective To study the effect of different concentration of tumor necrosis factor-α (TNF-α) on expression of the receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin (OPG) mRNA on human dental follicle cells in vitro, and investigate the...
核因子κB受体活化剂配体RANKL1. Objective:To observe the expression of the receptor activator of the nuclear factor-kappa B ligand(RANKL) mRNA at the occlusal surface of tooth germ in rat mandibular first molar and the differentiation of osteoclast. 目的:探讨核因子κB受体活化剂配体RANKL在大鼠下...
核因子kappa B受体活化因子RANK配体龈沟液目的:探讨正畸保持期牙周龈沟液中骨保护素(osteoprotegerin,OPG)和核因子kappa B受体活化因子配体水平(receptor activator of nuclear factor kappa B ligand,RANKL)的变化及相应牙周组织OPG和RANKL表达的变化,为预测保持期牙周骨组织状态是否稳定提供依据.方法:选...
核因子-κB受体活化因子配体 1. Objective To study the effects of tumor necrosis factor-alpha(TNF-α)on the gene expression of receptor activator of nuclear factor-κB ligand(RANKL) and osteoprotegerin(OPG) in human periodontal ligament fibroblasts(HPDLFs). 目的探讨肿瘤坏死因子-α(TNF-α)对人...