顺铂(Cisplatin)是一种有效的铂基抗肿瘤药,用作细胞凋亡诱导剂和半胱天冬酶-3激活剂。 图1.Cisplatin化学结构 Cisplatin基础信息 中文名:顺铂; 顺式二氨合铂(II)二氯化物; 布里铂; 新铂; 柏拉图素; 莱德铂; 顺式 DDP 铂; 英文名:cisplatin;cis-Diammineplatinum dichloride; cis-Diammineplatinum(II) dichl...
Ikarugamycin(伊卡鲁霉素)是一种大环抗生素,首先从 Streptomyces sp. 中分离出来,显示出强大的抗原生动物活性。它在癌细胞系中表现出细胞毒性作用,通过基因毒性和诱导细胞凋亡和半胱天冬酶活化来抑制细胞增殖(在 HL-60 细胞中 IC50 = 221.3 nM)。它还显示出显着抑制氧化低密度脂蛋白诱导的 1-4 μM 巨噬细胞中...
半胱天冬酶-3酶原 1. The expression of procaspase-3 in hippocampus following transient forebrain ischemia was explored,and the possible relationship of ischemia/reperfusion and procaspase-3 activation was observed. 通过测定脑缺血再灌注时海马中半胱天冬酶-3酶原(procaspase-3)的表达变化,从细胞凋亡的角...
半胱天冬氨酸蛋白酶-3 1. Objective: Investigating the expression of Caspase-3 mRNA by reverse transcription polymerasechain reaction(RT-PCR) in the normal and preeclampsia placentas in order to evaluate the role of Caspase-3 in preeclampsia. 目的检测半胱天冬氨酸蛋白酶-3(Caspase-3)mRNA在子痫前...
半胱天冬酶-3酶原 1. The expression of procaspase-3 in hippocampus following transient forebrain ischemia was explored,and the possible relationship of ischemia/reperfusion and procaspase-3 activation was observed. 通过测定脑缺血再灌注时海马中半胱天冬酶-3酶原(procaspase-3)的表达变化,从细胞凋亡的角...
半胱天冬酶-3、Bcl-2在扁平苔藓皮损中的表达 2. OBJECTIVE To investigate the inhibiton of polypeptide from Chlamys farreri (PCF) on UVA-induced HaCaT cells apoptosis through p38 mitogen activated protein kinase (MAPK) pathway and caspase-3. 目的从p38促细胞分裂剂激活性蛋白激酶(p38MAPK)通路和半胱...
半胱天冬酶-3、Bcl-2在扁平苔藓皮损中的表达 2. OBJECTIVE To investigate the inhibiton of polypeptide from Chlamys farreri (PCF) on UVA-induced HaCaT cells apoptosis through p38 mitogen activated protein kinase (MAPK) pathway and caspase-3. 目的从p38促细胞分裂剂激活性蛋白激酶(p38MAPK)通路和半胱...