Zips, M. Baumann, gammaH2AX assay in ex vivo irradiated tumour specimens: a novel method to determine tumour radiation sen- sitivity in patient-derived material, Radiother. Oncol. (2015).Menegakis, A.; Von Neubeck, C.; Yaromina, A.; Thames, H.; Hering, S.; Hennenlotter, J.; ...
Although faster than the 'gold standard' dicentric assay, conventional sample processing and foci analysis is still impractical when large numbers of people may need to be screened. To deal with such a situation, two gamma-H2AX assay formats with high throughput capacity have been developed and ...
Assay for large range of human and animal tissues, reconstructive tissues RHE in development Simultaneous answer about Cytotoxic Effect of test compound Short turnaround time 14 days Higher sensitivity and specificity as compared to Micronucleus Assay ...
Assay-dependent - 产品规格 种属反应 Human,Mouse 宿主/亚型 Rabbit / IgG Expression System HEK293 cells 分类 Recombinant Monoclonal 类型 Antibody 克隆号 BLR053F 抗原 Peptide surrounding phosphorylated serine 140 of human histone H2AX. 查看免疫原 ...
1C,D). Western blotting assay also showed that Wip1 KO mice exhibited increased γ-H2AX level in the hippocampus compared to the control group (P < 001; Fig. 1E,F). These data demonstrate that embryonic Wip1 deficiency leads to the upregulation of the phosphorylated H2AX (i.e., ...
The gamma-H2Ax assay is used to count radiation-induced DNA DSBs in peripheral blood lymphocytes (PBLs) in the evaluation of both diagnostic and therapeutic medicine modalities such as radiotherapy [[7], [8], [9]], computed tomography [[10], [11], [12], [13]], diagnostic nuclear ...
上海玉博生物科技有限公司做为thermo代理商之产品A700-053-gamma-H2AX Recombinant Rabbit Monoclonal Antibody (BLR053F)的产品销售公司,专业经营原装进口抗体(单克隆、多克隆)、重组蛋白、检测试剂盒、标准品、细胞因子、胎牛血清、细胞培养类等生物试剂以及耗材。
Measurement of gamma-H2AX protein changes in the peripheral blood lymphocytes (PBL) of individuals exposed to ionizing radiation is a simple, sensitive, and rapid assay for radiation triage and early marker of dose estimation. The qualitative and quantitative measurements of the protein changes were ...
ATRIP: ATR-interacting protein BRCA1: Breast cancer associated 1 DNA-PK: DNA-dependent protein kinase DSBs: DNA double-strand breaks ECVAM: European Centre for the Validation of Alternative Methods ELISA: Enzyme-linked immunosorbent assay HR: ...
-H2AX assay, were similar to those observed in their human counterparts. To substantiate the similarity observed between the human and minipig we show that minipig fibroblast radiosensitivity was similar to that observed with human fibroblasts. Finally, a strong ?-H2AX induction was observed in ...